Table 1

Population characteristics at baseline in the 3C-Dijon MRI cohort (N=1714)

Variablen%
Female104260.8
Male67239.2
Median age in years, IQR7269–76
Married101359.1
Not married70040.8
Bachelor degree55332.3
Other education115967.6
BMI <25 kg/m²84149.0
BMI 25–30 kg/m²67739.5
BMI >30 kg/m²19511.4
Median systolic BP mm Hg, IQR149.5133–162.5
Median diastolic BP mm Hg, IQR84.577–92
Antihypertensive drug use73042.6
Cardiovascular disease714.1
FPG ≥7.0 mmol/L1408.2
Median LDL cholesterol mmol/L, IQR3.532.99–4.06
Median HDL cholesterol mmol/L, IQR1.611.37–1.90
Current tobacco smoker975.7
Former tobacco smoker55932.6
Alcohol use (standard drinks per week), IQR71–14
Psychotropic drug use39923.3
Depression symptoms22112.9
Median MMSE score, IQR2827–29
Median Benton score, IQR1211–13
Total autonomy (living independently)162895.0
Dependence for at least one instrumental activity of daily living714.1
Gait imbalance33219.4
Forgetfulness84949.5
Difficulties retaining new simple information68139.7
Difficulties with simple arithmetic calculations27516.1
Difficulties with language or comprehension109764.0
MRI parameters
 Median no of WML, IQR155120–197
 Median WML volume cm3, IQR4.012.75–6.37
 Median no of deep WML, IQR5742–81
 Median deep WML volume cm3, IQR1.160.75–1.79
 Median no of periventricular WML, IQR9574–121
 Median periventricular WML volume cm3, IQR2.771.82–4.65
  • BMI, body mass index; BP, blood pressure; FPG, fasting plasma glucose; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MMSE, Mini-Mental State Examination; WML, white matter lesions.