Table 6

Frequency of health outcomes in the STRONG TM cohort relative to comparison groups

Health outcomesTM cohort, n (%)*Reference males, n (%)*Reference females, n (%)*
Cardiovascular disease
 Venous thromboembolism45 (1.6)266 (0.9)356 (1.2)
 Stroke42 (1.5)360 (1.3)250 (0.9)
 Myocardial infarction17 (0.6)210 (0.7)88 (0.3)
 Peripheral artery disease38 (1.3)309 (1.1)242 (0.8)
 Unstable angina20 (0.7)215 (0.8)123 (0.4)
Mental health†
 Anxiety1323 (46)3583 (13)6089 (21)
 Depression1594 (55)3806 (13)6813 (24)
 Self-inflicted injury‡121 (4.2)109 (0.4)181 (0.6)
 Suicidal ideation193 (6.7)160 (0.6)186 (0.7)
 Substance abuse disorder418 (14)2391 (8.4)1523 (5.3)
Cancer primary site
 Breast20 (0.7)¶ 217 (0.8)
 Cervix7 (0.2)0 (0.0)172 (0.6)
 Melanoma8 (0.3)109 (0.4)71 (0.2)
Other chronic conditions†
 HIV§9 (0.3)117 (0.4)10 (0.0)
 Diabetes153 (5.3)1329 (4.7)1213 (4.2)
Vital status
 Alive2853 (99)28 237 (99)28 366 (99)
 Dead39 (1.3)283 (1.0)183 (0.6)
Total2892 (100)28 520 (100)28 549 (100)
  • *Percentages do not add to 100% due to overlapping categories.

  • †Based on at least two diagnoses in the EMR.

  • ‡Combined diagnoses of self-inflicted injury, self-inflicted injury/poisoning and possible self-inflicted injury.

  • §HIV status ascertained from disease registries in Kaiser Permanente health plans located in Northern and SouthernCalifornia and from two or more International Classification of Diseases codes in the EMR in Kaiser Permanente health plan located in Georgia.

  • ¶Counts <5 are suppressed.

  • EMR, electronic medical record; STRONG, Study of Transition, Outcomes and Gender; TM, transmasculine.