Antibiotic use | Hypoglycaemia in the first 48 hours of life | Phototherapy in the first 72 hours of life | Transient tachypnoea of the newborn | Phototherapy after hospital discharge | |||||||||||
% | OR | AOR* (95% CI) | % | OR | AOR* (95% CI) | % | OR | AOR* (95% CI) | % | OR | AOR* (95% CI) | % | OR | AOR* (95% CI) | |
Spontaneous† | |||||||||||||||
All | |||||||||||||||
37 weeks (n=1219) | 1.8 | 1.06 | 1.06 (0.63 to 1.77) | 0.7 | 2.61 | 2.53 (1.09 to 5.89) | 2.4 | 1.22 | 1.22 (0.75 to 1.99) | 1.8 | 1.43 | 1.42 (0.88 to 2.28) | 5.8 | 2.07 | 2.11 (1.42 to 3.13) |
38 weeks (n=3213) | 1.6 | 0.95 | 0.92 (0.57 to 1.48) | 0.7 | 2.44 | 2.22 (0.99 to 4.95) | 1.7 | 0.85 | 0.86 (0.61 to 1.22) | 1.4 | 1.06 | 1.02 (0.62 to 1.70) | 3.7 | 1.29 | 1.30 (0.93 to 1.84) |
39/40 weeks (n=6178) | 1.7 | Reference | 0.3 | Reference | 2.0 | Reference | 1.3 | Reference | 2.9 | Reference | |||||
No maternal or fetal conditions | |||||||||||||||
37 weeks (n=1027) | 1.8 | 1.18 | 1.18 (0.66 to 2.12) | 0.7 | 3.05 | 2.86 (1.11 to 7.46) | 2.4 | 1.48 | 1.48 (0.88 to 2.51) | 1.8 | 1.67 | 1.69 (0.95 to 3.00) | 5.4 | 2.00 | 2.00 (1.26 to 3.15) |
38 weeks (n=2743) | 1.5 | 0.92 | 0.90 (0.53 to 1.52) | 0.6 | 2.56 | 2.29 (0.85 to 6.21) | 1.6 | 0.99 | 1.01 (0.69 to 1.46) | 1.2 | 1.14 | 1.1 (0.64 to 1.9) | 3.2 | 1.14 | 1.16 (0.77 to 1.73) |
39/40 weeks (n=5195) | 1.6 | Reference | 0.2 | Reference | 1.6 | Reference | 1.1 | Reference | 2.8 | Reference | |||||
Maternal or fetal conditions‡ | |||||||||||||||
37 weeks (n=192) | 1.4 | 0.61 | 0.66 (0.18 to 2.37) | 0.8 | 1.52 | 2.04 (0.31 to 13.59) | 2.6 | 0.66 | 0.63 (0.22 to 1.78) | 1.8 | 0.79 | 0.78 (0.27 to 2.21) | 8.2 | 2.53 | 3.12 (1.46 to 6.66) |
38 weeks (n=470) | 2.5 | 1.11 | 1.05 (0.45 to 2.46) | 1.1 | 2.22 | 2.35 (0.39 to 14.04) | 2.1 | 0.54 | 0.55 (0.22 to 1.37) | 2.0 | 0.89 | 0.83 (0.29 to 2.38) | 6.7 | 2.00 | 2.14 (1.08 to 4.25) |
39/40 weeks (n=983) | 2.2 | Reference | 0.5 | Reference | 3.8 | Reference | 2.2 | Reference | 3.4 | Reference | |||||
Provider initiated | |||||||||||||||
All | |||||||||||||||
37 weeks (n=943) | 3.1 | 1.55 | 1.68 (1.03 to 2.76) | 1.1 | 5.41 | 5.54 (2.22 to 13.83) | 5.6 | 3.47 | 3.44 (2.29 to 5.17) | 3.4 | 2.01 | 2.07 (1.24 to 3.45) | 5.9 | 1.53 | 1.53 (1.03 to 2.28) |
38 weeks (n=2869) | 2.2 | 1.10 | 1.23 (0.78 to 1.94) | 1.0 | 4.52 | 4.88 (2.13 to 11.18) | 3.3 | 2.01 | 2.01 (1.41 to 2.86) | 1.9 | 1.12 | 1.13 (0.72 to 1.79) | 5.6 | 1.43 | 1.43 (1.03 to 2.00) |
39/40 weeks (n=4230) | 2.1 | Reference | 0.2 | Reference | 1.7 | Reference | 1.7 | Reference | 4.0 | Reference | |||||
No maternal or fetal conditions | |||||||||||||||
37 weeks (n=538) | 1.9 | 1.10 | 1.24 (0.63 to 2.44) | 0.8 | 7.51 | 7.86 (1.95 to 31.71) | 4.8 | 3.67 | 3.59 (1.95 to 6.60) | 2.8 | 3.02 | 2.98 (1.57 to 5.65) | 4.7 | 1.06 | 1.07 (0.62 to 1.85) |
38 weeks (n=1980) | 1.9 | 1.10 | 1.25 (0.72 to 2.18) | 0.6 | 5.11 | 5.76 (1.63 to 20.32) | 3.1 | 2.31 | 2.29 (1.49 to 3.53) | 2.0 | 2.13 | 2.12 (1.00 to 4.48) | 5.2 | 1.20 | 1.16 (0.81 to 1.67) |
39/40 weeks (n=3069) | 1.7 | Reference | 0.1 | Reference | 1.3 | Reference | 1.0 | Reference | 4.4 | Reference | |||||
Maternal or fetal conditions‡ | |||||||||||||||
37 weeks (n=405) | 4.9 | 1.64 | 1.65 (0.82 to 3.35) | 1.6 | 3.27 | 3.47 (1.03 to 11.7) | 6.7 | 2.73 | 2.78 (1.51 to 5.11) | 4.2 | 1.12 | 1.17 (0.57 to 2.39) | 7.4 | 2.75 | 2.91 (1.41 to 6.00) |
38 weeks (n=889) | 3.1 | 1.03 | 1.11 (0.51 to 2.43) | 1.9 | 3.84 | 4.26 (1.2 to 15.14) | 3.9 | 1.55 | 1.54 (0.86 to 2.75) | 1.8 | 0.47 | 0.47 (0.27 to 0.82) | 6.3 | 2.31 | 2.61 (1.43 to 4.79) |
39/40 weeks (n=1161) | 3.0 | Reference | 0.5 | Reference | 2.5 | Reference | 3.8 | Reference | 2.8 | Reference |
*Women with the following conditions: hypertensive disorders (chronic hypertension, pre-eclampsia and HELLP syndrome); eclampsia; pre-existing and gestational diabetes; renal, cardiac or autoimmune diseases; severe infection at admission for birth; placental abruption and placental praevia and fetuses with IUGR.
†Adjusted for capacity of hospital of birth, payment of birth, age, years of schooling, parity, previous caesarean section, history of stillbirth or neonatal death and mode of birth.
‡Spontaneous onset of labour or premature rupture of membranes.
AOR, adjusted OR; HELLP, haemolysis, elevated liver enzymes and low platelet count; IUGR, intraueterine growth restriction.