Chronic traumatic brain injury (TBI) | A spectrum of disorders associated with long-term consequences of single or repetitive TBI. |
Chronic traumatic encephalopathy (CTE)* | Prototypic chronic TBI, long-term neurological consequences of repetitive mild TBI. |
Dementia pugilistica | A subtype of CTE that is typically reserved for cases of severe end-stage dementia secondary to a long boxing career. |
Chronic postconcussion syndrome* | A condition in those athletes in whom post-concussion symptoms do not appear to resolve. |
Chronic neurocognitive impairment* | A rather diverse classification of chronic neurocognitive signs and symptoms secondary to head impact exposures and recurrent concussions that is theoretically distinctive from CTE. |
Post-traumatic dementia† | Cases in which the athlete meets clinical criteria for dementia secondary to a single moderate-to-severe TBI. |
Post-traumatic cognitive impairment† | Individuals who sustain long-term neurocognitive deficits from a single moderate-to-severe brain injury and do not meet clinical criteria for dementia, but instead mild cognitive impairment. |
Post-traumatic parkinsonism | A Parkinsonian-like syndrome secondary to a single moderate-to-severe or repetitive TBI, occurring solely or as a component of CTE. |
*The most clinically pertinent examples of sports-related chronic TBI.
†Consequence of a single brain injury.