OR and 95% CI between hyperuricaemia and AF prevalence
| Group | Subjects (n) | AF | Prevalence (%) | Unadjusted model | Adjusted model | ||
| OR (95% CI) | P value | OR (95% CI) | P value | ||||
| Men* | 4686 | 35 | 0.74 | ||||
| Normal SUA level | 3844 | 29 | 0.75 | 1.000 | 1.0000 | 1.000 | 1.0000 |
| Hyperuricaemia | 842 | 6 | 0.71 | 0.944 (0.391 to 2.281) | 0.90 | 1.025 (0.400 to 2.626) | 0.96 |
| Women* | 4251 | 18 | 0.42 | ||||
| Normal SUA level | 3896 | 11 | 0.28 | 1.000 | 1.0000 | 1.000 | 1.0000 |
| Hyperuricaemia | 355 | 7 | 1.97 | 7.104 (2.737 to 18.442) | <0.001 | 6.366 (2.553 to 15.871) | <0.001 |
| Total † | 8937 | 53 | 0.60 | ||||
| Normal SUA level | 7740 | 40 | 0.52 | 1.000 | 1.0000 | 1.000 | 1.0000 |
| Hyperuricaemia | 1197 | 13 | 1.09 | 2.114 (1.128 to 3.964) | 0.02 | 2.051 (1.063 to 3.856) | 0.03 |
| Sensitive analysis | |||||||
| Total ‡ | |||||||
| Normal SUA level | 5525 | 17 | 0.31 | 1.000 | 1.0000 | 1.000 | 1.0000 |
| Hyperuricaemia | 635 | 9 | 1.42 | 4.658 (2.068 to 10.494) | <0.001 | 5.666 (2.383 to 13.473) | <0.001 |
| Total § | |||||||
| Normal SUA level | 7699 | 37 | 0.48 | 1.000 | 1.0000 | 1.000 | 1.0000 |
| Hyperuricaemia | 1191 | 13 | 1.09 | 2.285 (1.211 to 4.312) | 0.01 | 2.183 (1.132 to 4.212) | 0.02 |
*Model 1: adjusted for age, smoking, alcohol use, diuretics use, statins use, hypertension, diabetes, MI, TIA/stroke and dyslipidaemia, heart failure and gout.
†Model 2: adjusted for model 1 and sex.
‡Model 3: adjusted for model 2 and further excluded subjects with hypertension.
§Model 4: adjusted for model 2 and further excluded subjects with MI or heart failure.
AF, atrial fibrillation; MI, myocardial infarction; SUA, serum uric acid; TIA, transient ischaemic attack.