Predictors | Anaemia | Folate deficiency | Vitamin B12 deficiency | |||||||||
Unadjusted | Adjusted | Unadjusted | Adjusted | Unadjusted | Adjusted | |||||||
RR (95% CI) | P value | RR (95% CI) | P value | RR (95% CI) | P value | RR (95% CI) | P value | RR (95% CI) | P value | RR (95% CI) | P value | |
Area of residence | ||||||||||||
Rural | 1.01 (0.99 to 1.02) | 0.222 | 0.99 (0.97 to 1.02) | 0.614 | 0.94 (0.87 to 1.02) | 0.192 | 0.95 (0.85 to 1.05) | 0.304 | 0.99 (0.92 to 1.08) | 0.973 | 0.81 (0.66 to 1.00) | 0.048 |
Urban | Ref | Ref | Ref | Ref | Ref | Ref | ||||||
Province | ||||||||||||
Punjab | Ref | Ref | Ref | Ref | Ref | Ref | ||||||
Sindh | 1.09 (1.07 to 1.11) | <0.001 | 1.07 (1.04 to 1.09) | <0.001 | 1.01 (0.92 to 1.12) | 0.768 | 0.94 (0.84 to 1.06) | 0.328 | 0.89 (0.80 to 0.98) | 0.022 | 1.25 (1.01 to 1.55) | 0.043 |
Khyber Pakhtunkhwa | 0.91 (0.88 to 0.94) | <0.001 | 0.93 (0.89 to 0.96) | <0.001 | 0.67 (0.58 to 0.79) | <0.001 | 0.77 (0.66 to 0.91) | 0.002 | 1.26 (1.13 to 1.41) | <0.001 | 1.25 (1.11 to 1.43) | <0.001 |
Balochistan | 1.00 (0.96 to 1.05) | 0.912 | 0.97 (0.92 to 1.02) | 0.262 | 1.06 (0.92 to 1.21) | 0.413 | 1.05 (0.90 to 1.24) | 0.536 | 0.80 (0.69 to 0.93) | 0.004 | 1.33 (0.47 to 3.77) | 0.587 |
Federally Administered Tribal Areas | 1.00 (0.95 to 1.05) | 0.924 | 0.99 (0.93 to 1.06) | 0.825 | 0.75 (0.54 to 1.04) | 0.083 | 0.85 (0.60 to 1.20) | 0.349 | 1.06 (0.87 to 1.29) | 0.556 | 1.04 (0.86 to 1.27) | 0.554 |
Azad Jammu and Kashmir | 0.95 (0.91 to 0.99) | 0.008 | 0.93 (0.88 to 0.98) | 0.005 | 0.52 (0.37 to 0.74) | <0.001 | 0.52 (0.37 to 0.75) | <0.001 | 1.17 (1.03 to 1.32) | 0.018 | 1.50 (1.08 to 2.08) | 0.015 |
Gilgit-Baltistan | 0.83 (0.79 to 0.87) | <0.001 | 0.81 (0.76 to 0.85) | <0.001 | 0.97 (0.81 to 1.17) | 0.761 | 0.96 (0.74 to 1.23) | 0.733 | 1.05 (0.94 to 1.18) | 0.374 | 1.28 (0.79 to 2.09) | 0.317 |
Household SES quintiles | ||||||||||||
Poorest | 1.09 (1.06 to 1.12) | <0.001 | 1.03 (0.99 to 1.07) | 0.172 | 1.07 (0.96 to 1.19) | 0.176 | 1.08 (0.92 to 1.26) | 0.328 | 0.88 (0.80 to 0.98) | 0.021 | 1.21 (0.83 to 1.77) | 0.329 |
Poorer | 1.03 (1.01 to 1.06) | 0.005 | 1.02 (0.98 to 1.05) | 0.318 | 0.98 (0.88 to 1.09) | 0.731 | 1.05 (0.91 to 1.21) | 0.497 | 0.93 (0.85 to 1.03) | 0.208 | 1.37 (0.96 to 1.94) | 0.080 |
Middle | 1.03 (1.00 to 1.05) | 0.016 | 1.01 (0.98 to 1.04) | 0.500 | 0.97 (0.88 to 1.06) | 0.571 | 1.02 (0.91 to 1.14) | 0.78 | 1.03 (0.95 to 1.12) | 0.418 | 1.21 (0.88 to 1.68) | 0.241 |
Richer | 1.01 (0.99 to 1.04) | 0.215 | 0.99 (0.96 to 1.02) | 0.429 | 0.97 (0.89 to 1.06) | 0.621 | 0.99 (0.89 to 1.09) | 0.774 | 0.96 (0.89 to 1.05) | 0.464 | 1.10 (0.81 to 1.50) | 0.542 |
Richest | Ref | Ref | Ref | Ref | Ref | Ref | ||||||
Food security | ||||||||||||
Food secure | Ref | Ref | Ref | Ref | Ref | Ref | ||||||
Food insecure without hunger | 1.03 (1.01 to 1.05) | <0.001 | 1.01 (0.99 to 1.04) | 0.290 | 1.02 (0.95 to 1.09) | 0.536 | 0.97 (0.89 to 1.06) | 0.562 | 0.93 (0.87 to 0.99) | 0.026 | 1.05 (0.85 to 1.30) | 0.622 |
Food insecure with hunger moderate | 1.07 (1.05 to 1.09) | <0.001 | 1.03 (1.00 to 1.06) | 0.027 | 1.10 (1.03 to 1.19) | 0.005 | 1.02 (0.92 to 1.13) | 0.71 | 0.90 (0.84 to 0.97) | 0.007 | 1.09 (0.89 to 1.35) | 0.397 |
Food insecure with hunger severe | 1.07 (1.05 to 1.10) | <0.001 | 1.01 (0.98 to 1.04) | 0.555 | 1.09 (1.00 to 1.19) | 0.046 | 0.99 (0.87 to 1.13) | 0.901 | 0.88 (0.81 to 0.96) | 0.005 | 1.07 (0.80 to 1.43) | 0.651 |
Age | ||||||||||||
15–19 years | 0.99 (0.93 to 1.06) | 0.943 | – | 1.15 (0.97 to 1.37) | 0.103 | – | 1.07 (0.89 to 1.28) | 0.431 | – | |||
20–29 years | Ref | Ref | Ref | |||||||||
30–39 years | 0.99 (0.98 to 1.01) | 0.649 | – | 0.98 (0.93 to 1.03) | 0.494 | – | 1.00 (0.95 to 1.05) | 0.965 | – | |||
40–49 years | 1.03 (1.01 to 1.06) | 0.004 | – | 1.00 (0.92 to 1.09) | 0.916 | – | 0.98 (0.90 to 1.06) | 0.655 | – | |||
Education | ||||||||||||
Illiterate | 1.02 (1.01 to 1.04) | <0.001 | – | 1.00 (0.94 to 1.06) | 0.976 | – | 0.97 (0.91 to 1.03) | 0.390 | – | |||
Literate | Ref | Ref | Ref | |||||||||
Occupation | ||||||||||||
Employed | 0.97 (0.94 to 0.99) | 0.049 | – | 0.85 (0.78 to 0.93) | <0.001 | – | 1.07 (0.96 to 1.19) | 0.205 | – | |||
Unemployed | Ref | Ref | Ref | |||||||||
No of pregnancies | ||||||||||||
≤4 | Ref. | Ref. | Ref. | Ref. | ||||||||
>4 | 1.03 (1.02 to 1.05) | <0.001 | 1.03 (1.01 to 1.05) | 0.002 | 1.05 (1.00 to 1.10) | 0.034 | – | 0.92 (0.87 to 0.97) | 0.002 | – | ||
Use of iron folate/folic acid/MMN during last pregnancy | ||||||||||||
Yes | 0.96 (0.95 to 0.97) | <0.001 | – | 0.98 (0.92 to 1.03) | 0.519 | – | 0.98 (0.93 to 1.03) | 0.526 | – | |||
No | Ref | Ref | Ref | |||||||||
Birth interval | ||||||||||||
≥36 month | Ref | Ref | Ref | |||||||||
<36 month | 1.00 (0.98 to 1.03) | 0.516 | – | 1.02 (0.93 to 1.13) | 0.562 | – | 0.96 (0.88 to 1.06) | 0.523 | – | |||
Worm Infestation | ||||||||||||
Yes | 1.02 (0.97 to 1.06) | 0.332 | – | 1.07 (0.92 to 1.23) | 0.335 | – | 0.89 (0.75 to 1.05) | 0.194 | 1.44 (0.95 to 2.17) | 0.087 | ||
No | Ref | Ref | Ref | Ref | ||||||||
Intake of green leafy vegetables | ||||||||||||
Daily | 0.93 (0.90 to 0.96) | <0.001 | 0.98 (0.94 to 1.02) | 0.363 | 0.78 (0.68 to 0.89) | <0.001 | 0.86 (0.74 to 1.01) | 0.924 | 1.07 (0.96 to 1.20) | 0.187 | – | |
Weekly | 0.98 (0.96 to 1.00) | 0.105 | 0.98 (0.95 to 1.00) | 0.043 | 0.97 (0.89 to 1.05) | 0.471 | 1.00 (0.92 to 1.10) | 0.062 | 0.98 (0.91 to 1.05) | 0.594 | – | |
Monthly | Ref | Ref | Ref | Ref | Ref | |||||||
Intake of red meat | ||||||||||||
Daily | 0.96 (0.88 to 1.03) | 0.306 | – | 1.05 (0.83 to 1.32) | 0.670 | – | 0.80 (0.60 to 1.07) | 0.134 | – | |||
Weekly | 0.97 (0.95 to 0.99) | 0.003 | – | 0.99 (0.93 to 1.05) | 0.857 | – | 1.00 (0.94 to 1.07) | 0.783 | – | |||
Monthly | Ref | Ref | Ref | |||||||||
Regular consumption of tea | ||||||||||||
<3 times per day | Ref | Ref | Ref | Ref | ||||||||
≥3 times per day | 0.97 (0.92 to 1.01) | 0.228 | – | 0.94 (0.79 to 1.12) | 0.514 | – | 0.87 (0.73 to 1.04) | 0.150 | 0.78 (0.59 to 1.04) | 0.094 | ||
Intake of dairy products | ||||||||||||
Daily | 1.03 (0.99 to 1.07) | 0.123 | 1.03 (0.98 to 1.08) | 0.234 | 0.90 (0.78 to 1.03) | 0.141 | – | 1.09 (0.92 to 1.28) | 0.287 | – | ||
Weekly | 1.04 (1.00 to 1.09) | 0.031 | 1.04 (0.99 to 1.09) | 0.087 | 0.94 (0.81 to 1.07) | 0.384 | – | 1.12 (0.95 to 1.31) | 0.156 | – | ||
Monthly | Ref | Ref | Ref | Ref | ||||||||
Intake of egg | ||||||||||||
Daily | 0.97 (0.94 to 1.00) | 0.155 | – | 0.80 (0.72 to 0.89) | <0.001 | 0.89 (0.81 to 0.98) | 0.022 | 1.08 (0.9 to 1.21) | 0.148 | – | ||
Weekly | 0.98 (0.95 to 1.00) | 0.183 | – | 0.85 (0.78 to 0.93) | <0.001 | 0.88 (0.78 to 0.99) | 0.032 | 1.01 (0.92 to 1.11) | 0.785 | – | ||
Monthly | Ref | Ref | Ref | |||||||||
BMI of women | ||||||||||||
Underweight (<18.5) | 1.03 (1.01 to 1.05) | <0.001 | 1.03 (1.00 to 1.05) | 0.023 | 1.07 (1.00 to 1.14) | 0.032 | – | 0.92 (0.85 to 0.99) | 0.031 | – | ||
Normal (18.5–24.99) | Ref | Ref | Ref | Ref | ||||||||
Overweight/obesity (>25) | 0.93 (0.91 to 0.94) | <0.001 | 0.95 (0.93 to 0.97) | <0.001 | 1.00 (0.94 to 1.07) | 0.851 | – | 1.07 (1.01 to 1.13) | 0.010 | – |
BMI, body mass index; MMN, multiple micronutrients; SES, socioeconomic status.