Table 1

General characteristics of the included studies

RCTs’ characteristicsDiabetes type 1
RCTs (n=231)
Journals’ impact factorHigh (≥8.42)59 (25.5)
Medium (≥2.57 and <8.42)115 (49.8)
Low (<2.57)42 (18.2)
Unknown15 (6.5)
Age rangeRange of actual age (years)1–21
Range of mean (years)2.9–17.7
Type of designParallel177 (76.6)
Crossover54 (23.4)
Sample sizeRange7–689
Mean (SD)Mean: 91.37 (103.38)
Median (IQR)Median: 51.5 (30–110.75)
Type of interventionInsulin/drug based91 (39.4)
Diet based21 (9.1)
Education based41 (17.7)
Other medical intervention17 (7.4)
Others61 (26.4)
ControlsPlacebo29 (12.5)
Usual care/no treatment/waitlist97 (42)
Other treatment105 (45.5)
  • Data are presented as n (%).

  • RCT, randomised controlled trial.