Table 2

Comorbidities, vital statistics and laboratory measurements among patients, stratified by body mass index (BMI) category

VariableN (%)* or
median (IQR)
BMI (kg/m2)
N (%)* or median (IQR)
<2525–29.930–34.9 (I)†35–39.9 (II)†≥40 (III)†
All subjects (% within row)324 199 (100.0%)68 424 (21.1%)121 287 (37.4%)75 199 (23.2%)34 152 (10.5%)25 137 (7.8%)
Diabetes49 346 (15.2%)3063 (4.5%)15 196 (12.5%)14 542 (19.3%)8779 (25.7%)7766 (30.9%)
Pre-diabetes33 130 (10.2%)602 (0.9%)12 886 (10.6%)10 319 (13.7%)5087 (14.9%)4236 (16.9%)
Hypertension138 874 (42.8%)15 854 (23.2%)49 460 (40.8%)38 558 (51.3%)19 435 (56.9%)15 567 (61.9%)
Systolic blood pressure (mm Hg)‡124 (114–135)118 (108–128)124 (114–134)126 (118–137)128 (120–138)130 (120–140)
Missing156 (0.0%)
Diastolic blood pressure (mm Hg)‡77 (70–83)72 (66–80)77 (70–82)79 (71–84)80 (72–85)80 (72–86)
Missing158 (0.0%)
Low-density lipoprotein (mg/dL)‡104 (84–126)99 (80–120)106 (85–128)106 (85–128)105 (84–127)104 (84–124)
Missing, n (%)60 448 (18.6%)
High-density lipoprotein (mg/dL)‡52 (42–65)65 (53–79)53 (44–64)48 (40–58)46 (38–56)45 (38–55)
Missing55 634 (17.2%)
Triglycerides (mg/dL)‡99 (70–144)74 (56–102)97 (69–139)114 (80–164)119 (85–169)117 (84–165)
Missing56 398 (17.4%)
Fasting blood glucose (mg/dL)‡,**93 (86–103)88 (82–94)97.5 (93–101)103.1 (95–106)107 (97–111)109.8 (97–114)
Missing177 139 (54.6%)
Random blood glucose (mg/dL)‡92 (84–103)88 (81–95)92 (85–101)95 (86–106)96 (86–111)97 (86–114)
Missing54 907 (16.9%)
Glomerular filtration§87.4 
(73.5–100.2)
92.0 
(78.2–105.1)
85.4 
(72.1–97.9)
85.4 
(71.8–98.0)
87.8 
(73.2–100.4)
91.5 
(76.1–104.6)
Missing29 061 (9.0%)
HbA1c (%)‡5.8 (5.5–6.5)5.6 (5.3–5.9)5.8 (5.5–6.3)5.9 (5.6–6.6)6.0 (5.6–6.8)6.0 (5.7– 6.9)
Missing207 248 (63.9%)
Cerebrovascular disease22 436 (6.9%)4120 (6.0%)9002 (7.4%)5465 (7.3%)2357 (6.9%)1492 (5.9%)
Coronary artery disease17 026 (5.3%)2210 (3.2%)6912 (5.7%)4769 (6.3%)1946 (5.7%)1189 (4.7%)
Heart failure¶5500 (1.7%)994 (1.5%)1801 (1.5%)1368 (1.8%)741 (2.2%)596 (2.4%)
  • Diabetes included patients with ICD-9 codes for type 1 or type 2 diabetes.

  • Pre-diabetes defined as having appropriate ICD-9 code within 2 years + one fasting glucose 100-125 mg/dL or at least two fasting glucose measurements of 100–125 mg/dL, or HbA1c 5.7%–6.4%.

  • Peripheral vascular disease was not included because it is inconsistently defined and not well-documented in medical records.

  • All measured associations between the weight classifications and the patient characteristics were statistically significant with a P value<0.0001.

  • *Except for ‘all subjects’ row, percentages reflect % within column (BMI) category.

  • †Obesity class.

  • ‡Median (IQR).

  • §Glomerular filtration rate calculated via Chronic Kidney Disease Epidemiology Collaboration.

  • ¶Heart failure recorded prior to 1 July 2013.

  • **Determination of ‘fasting’ blood glucose:serum blood glucose obtained at the same time of those who had recorded fasting hours.

  • ICD-9,  International Classification of Diseases, Ninth Revision.