Haplotype association analysis for rs2272127, rs2293225 and rs7559479 in the IL18RAP gene with the body mass index (BMI) and obesity risk adjusted for age and sex
| No | Haplotype | Frequency | Freq. | OR (95% CI) | P value | BMI | ||
| Non-obese | Obese | Difference (95% CI) | P value | |||||
| 1 | CCA | 0.344 | 0.308 | 0.337 | 1.00 | – | 0.00 | – |
| 2 | CCG | 0.220 | 0.277 | 0.232 | 1.44 (1.15 to 1.80) | 0.0015 | 0.48 (0.12 to 0.85) | 0.0088 |
| 3 | GCA | 0.225 | 0.232 | 0.226 | 1.13 (0.90 to 1.43) | 0.30 | 0.08 (−0.29 to 0.44) | 0.68 |
| 4 | CTA | 0.206 | 0.175 | 0.199 | 0.95 (0.74 to 1.21) | 0.68 | −0.2 (−0.57 to 0.17) | 0.29 |
SNPs used in the haplotype construction: rs2272127, rs2293225 and rs7559479.
Bold indicates significance.
Freq, frequency.