Type of pre-diabetes | Description | Diagnostic test used | Criteria for diagnosis | Incidence of T2DM (per person-year)12 | ||
WHO8 | ADA9 | IEC10 | ||||
Impaired glucose tolerance | High blood glucose 2 hours after a drink containing 75 g of sugar (eg, Lucozade) | Oral glucose tolerance test | 2 hours postload glucose of 7–11.1 mmol/L | 2 hours postload glucose of 7–11.1 mmol/L | N/A | 0.045 |
Impaired fasting glucose | High blood glucose following a period of fasting | Fasting plasma glucose | 6.0–6.9 mmol/L | 5.6–6.9 mmol/L | N/A | WHO criteria: 0.047 ADA criteria: 0.036 |
HbA1c ‘at risk’ range | Glycated haemoglobin which estimates blood glucose levels over the previous 2–3 months | HbA1c | 6.0%–6.4% | 5.7%–6.4% | 6.0%–6.4% | WHO criteria: 0.036 |
Impaired glucose tolerance and impaired fasting glucose | As above | Fasting plasma glucose and oral glucose tolerance test | 2 hours postload glucose: 7–11.1 mmol/L and fasting plasma glucose: 6.0–6.9 mmol/L | 2 hours postload glucose: 7–11.1 mmol/L and fasting plasma glucose: 5.6–6.9 mmol/L | N/A | 0.070 |
ADA, American Diabetes Association; IEC, International Expert Committee; N/A, Not applicable; T2DM, Type 2 Diabetes Mellitus.