Metabolic risk and body composition according to presence of hepatitis C virus (HCV) infection in men and women
| Males (n=777) | Females (n=490) | |||||
| Variable | HCV− (n=711) | HCV+ (n=66) | p Value | HCV− (n=445) | HCV+ (n=45) | p Value |
| Age (year) | 54.1 (12.2) | 60.6 (11.1) | <0.001* | 53.4 (11.4) | 59.4 (7.3) | <0.001* |
| BMI (kg/m2) | 25.3 (3.4) | 25.0 (3.2) | 0.524 | 23.2 (3.5) | 24.5 (3.3) | 0.021 |
| Waist circumstance (cm) | 87.2 (8.9) | 87.8 (9.2) | 0.631 | 76.2 (8.6) | 79.9 (9.8) | 0.007 |
| Waist to height ratio | 0.52 (0.05) | 0.52 (0.06) | 0.608 | 0.48 (0.06) | 0.51 (0.06) | 0.005 |
| SBP (mm Hg) | 128.8 (19.4) | 129.7 (19.2) | 0.725 | 122.7 (23.0) | 127.2 (23.4) | 0.214 |
| DBP (mm Hg) | 75.0 (12.0) | 74.0 (10.8) | 0.516 | 67.4 (11.5) | 68.9 (11.8) | 0.399 |
| MAP (mm Hg) | 92.9 (13.5) | 92.5 (12.3) | 0.831 | 85.8 (14.3) | 88.3 (14.5) | 0.262 |
| Fasting glucose (mg/dL) | 109.1 (31.8) | 109.5 (32.2) | 0.925 | 100.5 (24.2) | 115.5 (45.4) | <0.001* |
| Total cholesterol (mg/dL) | 196.9 (39.0) | 177.0 (32.5) | <0.001* | 204.2 (39.2) | 192.3 (33.7) | 0.051 |
| TG (mg/dL) | 148.5 (100.5) | 121.4 (55.6) | 0.031 | 109.2 (79.6) | 102.9 (50.0) | 0.600 |
| HDL-C (mg/dL) | 46.6 (12.3) | 43.6 (9.6) | 0.059 | 57.2 (13.6) | 55.5 (13.8) | 0.436 |
| TG/HDL-C ratio | 3.59 (3.07) | 3.05 (1.84) | 0.163 | 2.18 (2.25) | 2.09 (1.40) | 0.804 |
| ALT (U/L) | 34.4 (33.4) | 57.6 (55.1) | <0.001* | 24.4 (35.9) | 45.3 (39.5) | <0.001* |
| Body fat % | 24.7 (5.2) | 24.8 (4.9) | 0.924 | 30.0 (5.2) | 31.8 (4.7) | 0.027 |
| Fat-free mass (kg) | 54.1 (6.5) | 53.6 (6.1) | 0.512 | 40.2 (4.5) | 41.0 (4.6) | 0.227 |
| Muscle mass (kg) | 50.0 (6.1) | 49.4 (5.6) | 0.429 | 36.8 (4.0) | 37.6 (4.2) | 0.240 |
| Visceral fat area (cm2) | 129.2 (40.9) | 134.6 (38.7) | 0.310 | 70.2 (34.4) | 84.3 (39.6) | 0.010 |
| Visceral obesity, n (%) | 576 (81.0) | 59 (89.4) | 0.092 | 75 (16.9) | 13 (28.9) | 0.045 |
*Indicates p<0.0028, which equals 0.05/18 items.
ALT, alanine aminotransferase; BMI, body mass index; DBP, diastolic blood pressure; HDL-C, high-density lipoprotein cholesterol; MAP, mean arterial pressure; SBP, systolic blood pressure; TG, triglyceride.