Values95% CIValues95% CI
SENS1.0000.359 to 1.00SENS1.0000.284 to 1.000
SPEC1.0000.934 to 1.00SPEC0.9960.992 to 0.999
PREV0.0580.019 to 0.13PREV0.0020.001 to 0.006
PPV1.0000.271 to 0.605PPV0.4000.122 to 0.738
NPV1.0000.891 to 0.999NPV1.0000.997 to 1.000
LR+InfNaN–InfLR+268.000120.582 to 595.645
LR−0.0000.000–NaNLR−0.140NaN
MCC1.0000.670 to 1.000MCC0.6310.339 to 0.631
  • AE, acute encephalopathy; AST, aspartate aminotransferase; Inf, infinite; LR−, negative likelihood ratio; LR+, positive likelihood ratio; MCC, Matthews correlation coefficient; NPV, negative predictive value; NaN, not a number; PPV, positive predictive value; PREV prevalence; SENS, sensitivity; SPEC, specificity.