Values95% CIValues95% CI
SENS0.9170.615 to 0.998SENS0.6670.223 to 0.957
SPEC0.9860.927 to 1.000SPEC0.9480.936 to 0.959
PREV0.1400.074 to 0.231PREV0.0040.001 to 0.008
PPV0.9170.615 to 0.998PPV0.0460.013 to 0.114
NPV0.9860.927 to 1.000NPV0.9990.995 to 1.000
LR+67.8339.611 to 478.756LR+12.9007.056 to 23.583
LR−0.0840.0130 to 0.552LR−0.3510.113 to 1.090
MCC0.9030.682 to 0.973MCC0.1660.067 to 0.230
  • AE, acute encephalopathy; AST, aspartate aminotransferase; LR−, negative likelihood ratio; LR+, positive likelihood ratio; MCC, Matthews correlation coefficient; NPV, negative predictive value; PPV, positive predictive value; PREV prevalence; SENS, sensitivity; SPEC, specificity.