Patient characteristics
| Derivation cohort n=86 | Validation cohort n=1612 | |
| Age, months | ||
| Median (range) | 22 (4–159) | 23 (0–185) |
| Gender, n (%) | ||
| Male | 51 (59.3) | 950 (58.9) |
| Poor outcome, n (%) | 17 (24.6) | 15 (0.93) |
| Predictor variables, n (%) | ||
| Refractory status epilepticus | 27 (31.4) | 52 (3.2) |
| Consciousness disturbance or hemiplegia at 6 hours from onset | 13 (15.1) | 35 (2.2) |
| AST >90 IU/L within 6 hours of onset | 5 (5.8) | 10 (0.62) |
| High-risk group (fulfilling any of the predictor variables above, NSAE-CPR) | 37 (43.0) | 87 (5.4) |
AST, aspartate aminotransferase; NSAE-CPR, clinical prediction rule for neurological sequelae due to acute encephalopathy.