Association between prenatal diagnosis and risk of infant mortality for four specific congenital heart defects (CHDs), EPIdémiologie des CARDiopathies congénitales (EPICARD) Population-Based Cohort Study
CHD | Prenatal diagnosis | Infant mortality | Risk ratio | 95% CI | |||
n* | n† | % | 95% CI | ||||
Functionally univentricular heart‡ | No | 7 | 3 | 42.9 | 9.9 to 81.6 | ||
Yes | 32 | 17 | 53.1 | 34.7 to 70.9 | 1.2 | 0.5 to 3.1 | |
d-Transposition of the great arteries‡ | No | 24 | 1 | 4.2 | 0.1 to 21.1 | ||
Yes | 57 | 5 | 8.8 | 2.9 to 19.3 | 2.1 | 0.3 to 17.1 | |
Tetralogy of Fallot‡ | No | 18 | 2 | 11.1 | 1.4 to 34.7 | ||
Yes | 36 | 1 | 2.8 | 0.07 to 14.5 | 0.3 | 0.02 to 2.6 | |
Coarctation of the aorta‡ | No | 44 | 3 | 6.8 | 1.4 to 18.7 | ||
Yes | 29 | 2 | 6.9 | 0.8 to 22.8 | 1.0 | 0.2 to 5.7 |
*N = number of live births (denominator data).
†n= number of deaths (numerator data).
‡Cases with the specific International Paediatric and Congenital Cardiac Code for the given CHD; whether or not other CHD codes were also included, all cases with chromosomal or others anomalies were excluded.