Relationship between CTS severity and anxiety, depression and quality of life
| n | HADS anxiety Mean (SD) | Estimate (95% CI)* | HADS depression Mean (SD) | Estimate (95% CI)* | EQ-5D Mean (SD) | Estimate (95% CI)* | |
| CTS-6 score | |||||||
| 1.00 | 7 | 3.14 (2.61) | 1.57 (1.81) | 0.78 (0.32) | |||
| 1.01–2.00 | 134 | 5.04 (4.07) | 2.90 (3.12) | 0.77 (0.20) | |||
| 2.01–3.00 | 308 | 5.50 (4.05) | 3.86 (3.31) | 0.72 (0.20) | |||
| 3.01–4.00 | 241 | 6.87 (4.55) | 5.42 (3.99) | 0.60 (0.28) | |||
| 4.01–5.00 | 63 | 9.62 (5.48) | 1.11 (0.73 to 1.49) | 7.68 (4.44) | 1.43 (1.13 to 1.73) | 0.43 (0.34) | −0.10 (−0.12 to −0.08) |
| p<0.0001 | p<0.0001 | p<0.0001 | |||||
| R2=17.7% | R2=26.1% | R2=37.4% | |||||
| NCS grade | |||||||
| 1 | 150 | 6.78 (4.79) | 4.64 (4.10) | 0.66 (0.28) | |||
| 2 | 79 | 7.13 (4.78) | 4.78 (3.73) | 0.68 (0.25) | |||
| 3 | 202 | 6.44 (4.36) | 4.33 (3.77) | 0.68 (0.27) | |||
| 4 | 137 | 6.24 (4.54) | 4.80 (3.92) | 0.68 (0.26) | |||
| 5 | 159 | 5.18 (4.24) | 4.20 (3.80) | 0.66 (0.24) | |||
| 6 | 24 | 3.42 (3.09) | −0.26 (−0.49 to −0.03) | 4.08 (3.13) | −0.00 (−0.20 to 0.20) | 0.61 (0.26) | −0.01 (−0.03 to 0.01) |
| p=0.029 | p=0.983 | p=0.214 | |||||
| R2=14.3% | R2=17.1% | R2=28.4% | |||||
*Parameter estimate (95% Cl) from a linear model including gender, age, ethnicity, employment status, smoking status, units of alcohol per week, body mass index, duration of CTS and comorbidity score.
CTS, carpal tunnel syndrome; EQ-5D, EuroQol-5 dimension; HADS, Hospital Anxiety and Depression Scale; NCS, nerve conduction studies.