Table 4

Estimated lifetime costs per person sent an invite for screening at age 60 years, over 40-year time horizon

gFOBT (£)FIT 180 µg Hb/g faeces (base case) (£)FIT 150 µg Hb/g faeces (£)FIT 100 µg Hb/g faeces (£)FIT 40 µg Hb/g faeces (£)FIT 20 µg Hb/g faeces (£)
Kits returned (normal result)7.5920.5920.5320.3919.8819.49
Kits returned (positive result)0.170.440.490.611.051.40
Kits sent but not returned2.233.513.503.503.493.48
Total screening costs 9.98 24.54 24.53 24.50 24.42 24.37
Follow-up colonoscopy-related costs*45.6950.2356.3071.04123.77165.73
Surveillance colonoscopy-related costs*31.9243.1148.4363.59105.86131.13
Cost of colonoscopy-related adverse events0.080.100.120.150.250.31
Total colonoscopy-related costs 77.83 93.59 105.01 134.97 230.19 297.58
CRC A management (% of CRC management costs)46.7744.6743.8642.1137.3135.53
CRC B management (% of CRC management costs)135.15127.10123.79117.2498.5191.39
CRC C management (% of CRC management costs)231.69216.52210.16198.49164.33151.88
CRC D management (% of CRC management costs)435.99403.99390.37367.43298.71275.01
Total CRC management costs 849.59 792.27 768.18 725.26 598.85 553.82
Total costs 937.40 910.40 897.72 884.73 853.47 875.78
  • *Also includes the cost of specialist screening practitioner appointments for those not attending colonoscopy.

  • CRC, colorectal cancer; FIT, faecal immunochemical test; gFOBT, guaiac faecal occult blood test.