Table 3

Colonoscopy resource use and adverse events for a population of 582 218 people invited for screening, 40-year time horizon

Resource useCost (£)
gFOBTFIT 180 µg Hb/g faeces (base case)Difference
(FIT - gFOBT)
gFOBTFIT 180 µg Hb/g faeces (base case)Difference
(FIT - gFOBT)
Follow-up
 Colonoscopies without polypectomy28 07428 60352912 981 87512 963 904−17 970
 Colonoscopies with polypectomy for HR adenomas14 89419 94350498 541 71611 514 0912 972 375
 Colonoscopies with polypectomy for LR adenomas88868309−5785 079 0184 766 975−312 043
 Deaths at colonoscopy000142140−2
 Total number of follow-up colonoscopies51 85556 855500026 602 75129 245 1112 642 360
 Major bleeds requiring hospitalisation2123276888375687
 Perforation3335274 45677 6353178
Surveillance
 Colonoscopies without polypectomy10 84714 56737204 377 9635 917 0471 539 084
 Colonoscopies with polypectomy for LR adenomas67549064231010 864 10414 669 9283 805 823
 Colonoscopies with polypectomy for HR adenomas21 84129 30574643 340 1274 510 9351 170 809
 Deaths at colonoscopy000719625
 Total number of surveillance colonoscopies39 44252 93713 49418 582 26525 098 0066 515 741
 Major bleeds requiring hospitalisation16215538172681887
 Perforation1925639 05952 76913 710
Total number of colonoscopies 91 297 1 09 791 18 494 18 626 705 25 158 043 6 531 337
Total number of colonoscopies per 1000 people invited for screening at age 60 years 157 189 32 31 993 43 211 11 218
  • FIT, faecal immunochemical test; gFOBT, guaiac faecal occult blood test; HR, high risk; LR, low risk.