Prevalence ORs (PORs) and 95% CIs for predictors of increased mesothelin and calretinin assessed with univariate logistic regression models in 569 men of the Heinz Nixdorf Recall Study
| Variable | Effect | N* | Mesothelin ≥1.5 nM | Calretinin ≥1 ng/mL | ||||||
| n† | POR | 95% CI | n† | POR | 95% CI | |||||
| Age (years) | 569 | 24 | 1.09 | 1.02 | 1.17 | 34 | 1.01 | 0.95 | 1.06 | |
| Cancer past blood collection (reference: no) | Yes | 20 | 0 | – | 4 | 4.33 | 1.36 | 13.7 | ||
| C-reactive protein (mg/dL) (reference: within standard values) | Greater than standard value‡ | 137 | 11 | 3.02 | 1.30 | 7.01 | 9 | 1.13 | 0.51 | 2.48 |
| Fibrinogen (mg/dL) (reference: less than or equal to standard values) | Greater than standard value‡ | 98 | 9 | 3.06 | 1.30 | 7.21 | 6 | 1.03 | 0.41 | 2.55 |
| Cystatin C (mg/dL) (reference: less than or equal to standard value) | Greater than standard value‡ | 37 | 12 | 20.8 | 8.48 | 50.8 | 6 | 3.48 | 1.34 | 9.02 |
| Creatinine (mg/dL) (reference: less than or equal to standard value) | Greater than standard value‡ | 112 | 15 | 7.70 | 3.27 | 18.1 | 10 | 1.77 | 0.82 | 3.82 |
| Brain natriuretic peptide (pg/mL) (reference: within standard values) | Greater than standard value‡ | 52 | 8 | 5.69 | 2.31 | 14.0 | 6 | 2.28 | 0.90 | 5.79 |
| Haemoglobin (g/dL) (reference: greater than or equal to standard value) | Less than standard value‡ | 34 | 9 | 12.5 | 4.98 | 31.3 | 31 | 1.57 | 0.46 | 5.43 |
| Haematocrit (L/L) (reference: greater than or equal to standard value) | Less than standard value‡ | 81 | 11 | 5.74 | 2.48 | 13.3 | 6 | 1.32 | 0.53 | 3.28 |
| Red blood cells (x1012L) (reference: greater than or equal to standard value) | Less than standard value‡ | 116 | 12 | 4.24 | 1.85 | 9.71 | 9 | 1.44 | 0.65 | 3.18 |
| Hemoglobin A1c (%) (reference: less than or equal to standard values) | Greater than standard value‡ | 196 | 13 | 2.32 | 1.02 | 5.29 | 12 | 1.04 | 0.50 | 2.14 |
| Bronchial asthma (reference: no) | Yes | 18 | 1 | 1.35 | 0.17 | 10.6 | 4 | 4.95 | 1.54 | 16.0 |
| Bronchitis (reference: no) | Yes | 11 | 3 | 9.57 | 2.37 | 38.7 | 2 | 3.77 | 0.78 | 18.2 |
| Hypertension (reference: no) | Yes | 365 | 23 | 13.7 | 1.83 | 101.9 | 23 | 1.18 | 0.56 | 2.47 |
| Antihypertensive intake (reference: no) | Yes | 350 | 23 | 15.3 | 2.06 | 114.4 | 23 | 1.33 | 0.64 | 2.79 |
| Beta blocker intake (reference: no) | Yes | 200 | 16 | 3.92 | 1.65 | 9.34 | 18 | 2.18 | 1.09 | 4.38 |
Statistically significant results are marked in bold
*Men with effect.
†Men with positive marker result and effect.
‡The standard values of all blood parameters are given in table 1.