Table 1

Active RCTs on HOPE in OLT on (search date: 26 August 2017)

Trial numberStudy centreStudy typeEnrolmentDonor groupPrimary endpointComment
NCT03124641 (present trial)RWTH Aachen University, Aachen, GermanyRCT46ECD-DBDEarly graft function (peak ALT level)Recruiting
NCT01317342University of Zurich, Zurich, SwitzerlandRCT170*DBD
(ECD subgroup analysis only)
Major postoperative complications (Clavien grade≥III) and CCI*Recruiting
NCT02584283University of Groningen, Groningen, NetherlandsRCT156DCD
(Maastricht category III)
Incidence of symptomatic NASRecruiting
  • *Information based on personal communication.

  • ALT, alanine aminotransferase; CCI, comprehensive complication index; DBD, donation of the brain death; DCD, donation of the cardiac death; ECD, extended criteria donation; HOPE, hypothermic oxygenated machine perfusion; NAS, non-anastomotic biliary strictures; OLT, orthotopic liver transplantation; RCT, randomised controlled trial; RWTH, Rheinisch-Westfälische Technische Hochschule.