Table 1

Baseline characteristics of patients

Patient characteristicOverall (n=512)Study groupp Value*
Non-adherence (n=270)Adherence (n=242)
General characteristics
 Age, median (IQR) years68 (59; 79)70 (59; 80)66 (59; 79)0.160†
 Age≥65, n (%)298 (58.2)166 (61.5)132 (54.5)0.112
 Male, n (%)280 (54.7)139 (51.5)141 (58.3)0.124
 Health insurance, n (%)408 (79.7)229 (84.8)179 (74.0) 0.002
 Hospital length of stay, median (IQR) days9 (7; 12)9 (7; 12)9 (7; 12)0.811†
CAD risk factors
 CAD family history, n (%)29 (5.7)17 (6.3)12 (5.0)0.513
 Hypertension, n (%)411 (80.3)220 (81.5)191 (78.9)0.468
 Diabetes, n (%)119 (23.2)66 (24.4)53 (21.9)0.496
 Dyslipidemia, n (%)127 (24.8)68 (25.5)59 (24.4)0.833
 Smoking, n (%)196 (38.3)100 (37.0)96 (39.7)0.541
 Number of CAD risk factors, median (IQR)2 (1; 2)2 (1; 2)2 (1;2)0.643†
Medical history and comorbidities, n (%)
 Prior MI/stroke150 (29.3)76 (28.1)74 (30.6)0.546
 Prior PCI/CABG19 (3.7)9 (3.3)10 (4.1)0.633
 Prior heart failure137 (25.8)70 (25.9)62 (25.6)0.937
 Peptic ulcer197 (38.5)112 (41.5)85 (35.1)0.140
 Asthma/COPD22 (4.3)13 (4.8)9 (3.7)0.542
Hospital findings, n (%)
 Killip class II–IV61 (11.9)11 (4.1)50 (20.7) <0.001
 eGFR<60 mL/min/1.73 m2 223 (43.6)111 (41.1)112 (46.3)0.239
 eGFR<30 mL/min/1.73 m2 29 (5.7)15 (5.6)14 (5.8)0.911
 Heart rate<60 beats/min30 (5.9)12 (4.4)18 (7.4)0.150
 SBP<100 mm Hg56 (10.9)11 (4.1)45 (18.6) <0.001
 LVEF<40%57 (11.1)10 (3.7)47 (19.4) <0.001
 AV block II–III7 (1.4)5 (1.9)2 (0.8)0.455‡
 AST/ALT increased84 (16.4)43 (15.9)41 (16.9)0.757
 In-hospital GI bleeding11 (2.1)7 (2.6)4 (1.7)0.464
Discharge diagnosis, n (%)
 NSTEACS351 (68.6)186 (68.9)165 (68.2)0.863
 STEACS161 (31.4)84 (31.1)77 (31.98)
In-hospital revascularisation procedures, n (%)
 No PCI384 (75.0)218 (80.7)166 (68.6) 0.002
 PCI128 (25.0)52 (19.3)76 (31.4)
  • *Using the χ2 test if other tests were not mentioned.

  • †Using Mann-Whitney test.

  • ‡Using Fisher’s exact test.

  • ACS, acute coronary syndrome; AST/ALT, aspartate aminotransferase or alanine aminotransferase; AV, atrial ventricular; CABG, coronary artery bypass grafting; CAD, coronary artery disease; eGFR, estimated glomerular filtration rate; GI, gastrointestinal; LVEF, left ventricular ejection fraction; MI, myocardial infarction; NSTACS, non-ST-elevation acute coronary syndrome; PCI, percutaneous coronary intervention; SBP, systolic blood pressure; STEACS, ST-elevation acute coronary syndrome.