Baseline summary
| Variable | Whole cohort (n=17 705) | Weekday admission (n=13 378) | Weekend admission (n=4327) | p-Value | Missing (% of whole cohort) |
| Age at admission, mean (SD) | 66.0 (13.0) | 66.2 (13.0) | 65.5 (13.1) | 0.001 | 7 (0.04) |
| Male, n (%) | 12 530 (70.8) | 9410 (70.3) | 3120 (72.1) | 0.028 | 0 (0.00) |
| Caucasian, n (%) | 12 283 (69.4) | 9360 (70.0) | 2923 (67.6) | 0.003 | 4988 (28.2) |
| Admission diagnosis | |||||
| Acute coronary syndrome, n (%) | 15 427 (87.1) | 11 689 (87.4) | 3738 (86.4) | 0.097 | 0 (0.00) |
| Chest pain unknown cause, n (%) | 1759 (9.94) | 1316 (9.84) | 443 (10.2) | 0.461 | |
| Other, n (%) | 519 (2.93) | 373 (2.79) | 146 (3.37) | 0.053 | |
| Previous AMI, n (%) | 3768 (21.3) | 2907 (21.7) | 861 (19.9) | 0.011 | 109 (0.62) |
| Previous angina, n (%) | 3968 (22.4) | 3073 (23.0) | 895 (20.7) | 0.002 | 282 (1.59) |
| Hypertension, n (%) | 9392 (53.0) | 7153 (53.5) | 2239 (51.7) | 0.050 | 255 (1.44) |
| Hypercholesterolaemia, n (%) | 7166 (40.5) | 5458 (40.8) | 1708 (39.5) | 0.127 | 574 (3.24) |
| PVD, n (%) | 809 (4.57) | 626 (4.68) | 183 (4.23) | 0.234 | 85 (0.48) |
| Cerebrovascular disease, n (%) | 1270 (7.17) | 998 (7.46) | 272 (6.29) | 0.010 | 83 (0.47) |
| Asthma or COPD, n (%) | 2717 (15.3) | 2095 (15.7) | 622 (14.4) | 0.044 | 114 (0.64) |
| Chronic renal failure, n (%) | 691 (3.90) | 527 (3.94) | 164 (3.79) | 0.693 | 143 (0.81) |
| Heart failure, n (%) | 508 (2.87) | 379 (2.83) | 129 (2.98) | 0.649 | 159 (0.90) |
| Enzymes elevated, n (%) | 16 378 (92.5) | 12 304 (92.0) | 4074 (94.2) | <0.001 | 634 (3.58) |
| Previous/current smoker, n (%) | 11 892 (67.2) | 9021 (67.4) | 2871 (66.4) | 0.195 | 550 (3.11) |
| Cholesterol, mean (SD) | 4.77 (1.35) | 4.76 (1.35) | 4.82 (1.38) | 0.015 | 4590 (25.9) |
| Diabetes | |||||
| Dietary control, n (%) | 609 (3.44) | 464 (3.47) | 145 (3.35) | 0.749 | 126 (0.71) |
| Oral medicine, n (%) | 1870 (10.6) | 1394 (10.4) | 476 (11.0) | 0.293 | |
| Insulin, n (%) | 721 (4.07) | 571 (4.27) | 150 (3.47) | 0.023 | |
| Insulin and medication, n (%) | 297 (1.68) | 224 (1.67) | 73 (1.69) | 0.999 | |
| Previous PCI, n (%) | 2124 (12.0) | 1651 (12.3) | 473 (10.9) | 0.014 | 17 (0.10) |
| Previous CABG, n (%) | 959 (5.42) | 732 (5.47) | 227 (5.25) | 0.595 | 4 (0.02) |
| Systolic BP, mean (SD) | 135.3 (27.7) | 135.1 (27.5) | 135.8 (28.3) | 0.219 | 2574 (14.5) |
| Heart Rate, mean (SD) | 76.8 (19.3) | 76.5 (19.1) | 77.5 (19.8) | 0.006 | 2257 (12.7) |
| Admitting consultant | |||||
| Cardiologist, n (%) | 17 093 (96.5) | 12 929 (96.6) | 4164 (96.2) | 0.216 | 52 (0.29) |
| Other general physician, n (%) | 445 (2.51) | 325 (2.43) | 120 (2.77) | 0.230 | |
| Other, n (%) | 115 (0.65) | 88 (0.66) | 27 (0.62) | 0.895 | |
| Beta blocker, n (%) | 4670 (26.4) | 3555 (26.6) | 1115 (25.8) | 0.306 | 617 (3.48) |
| Statin, n (%) | 6997 (39.5) | 5360 (40.1) | 1637 (37.8) | 0.009 | 630 (3.56) |
| Glucose, mean (SD) | 8.60 (4.60) | 8.55 (4.61) | 8.76 (4.58) | 0.015 | 3044 (17.2) |
| Height, mean (SD) | 170.1 (9.76) | 170.0 (9.81) | 170.5 (9.57) | 0.011 | 3514 (19.8) |
| Weight, mean (SD) | 81.9 (18.7) | 81.8 (18.8) | 82.0 (18.3) | 0.624 | 2571 (14.5) |
| Family history of CHD, n (%) | 8287 (46.8) | 6273 (46.9) | 2014 (46.5) | 0.705 | 1939 (11.0) |
| Creatinine, mean (SD) | 95.7 (64.6) | 95.5 (63.3) | 96.3 (68.4) | 0.502 | 266 (1.50) |
| Haemoglobin, mean (SD) | 136.6 (19.1) | 136.3 (19.2) | 137.5 (18.8) | <0.001 | 195 (1.10) |
| Killip class | 6919 (39.1) | ||||
| No evidence of heart failure, n (%) | 9103 (51.4) | 6918 (51.7) | 2185 (50.5) | 0.170 | |
| Basal crepitations, n (%) | 811 (4.58) | 590 (4.41) | 221 (5.11) | 0.062 | |
| Pulmonary oedema, n (%) | 600 (3.39) | 453 (3.39) | 147 (3.40) | 0.999 | |
| Cardiogenic shock, n (%) | 266 (1.50) | 195 (1.46) | 71 (1.64) | 0.430 | |
| Cardiac arrest, n (%) | 1493 (8.43) | 1106 (8.27) | 387 (8.94) | 0.174 | 0 (0.00) |
| Thienopyridene, n (%) | 15 632 (88.3) | 11 774 (88.0) | 3858 (89.2) | 0.043 | 109 (0.62) |
| STEMI, n (%) | 9322 (52.7) | 6781 (50.7) | 2541 (58.7) | <0.001 | 496 (2.80) |
AMI, acute myocardial infarction; BP, blood pressure; CABG, coronary artery bypass graft; CHD, coronary heart disease; COPD, chronic obstructive pulmonary disease; LVEF, left ventricular ejection fraction; MI, myocardial infarction; PCI, percutaneous coronary intervention; PVD, peripheral vascular disease; STEMI, ST segment elevation myocardial infarction.