Values obtained after applying the new scoring on the original data set (internal validation) and the data set from institution 2 (cross-validation)
| Sn (95% CI) | Sp (95% CI) | PPV (95% CI) | NPV (95% CI) | PCC (95% CI) | ROC | ||
| Internal validation process | Cut-off of 6 | 0.888 (0.874 to 0.903) n=7250 | 0.883 (0.870 to 0.895) n=20 197 | 0.731 (0.709 to 0.752) n=8814 | 0.957 (0.950 to 0.963) n=18 633 | 0.884 (0.875 to 0.893) n=27 447 | 0.952 |
| Cut-off of 10 | 0.637 (0.587 to 0.686) n=950 | 0.992 (0.990 to 0.994) n=26 497 | 0.746 (0.694 to 0.798) n=811 | 0.987 (0.984 to 0.990) n=26 636 | 0.980 (0.977 to 0.983) n=27 447 | 0.982 | |
| Cross-validation process | Cut-off of 6 | 0.860 (0.845 to 0.876) n=5784 | 0.873 (0.860 to 0.887) n=6969 | 0.849 (0.833 to 0.866) n=5859 | 0.883 (0.867 to 0.899) n=6894 | 0.867 (0.859 to 0.876) n=12 753 | |
| Cut-off of 10 | 0.525 (0.491 to 0.559) n=1813 | 0.986 (0.983 to 0.988) n=10 940 | 0.858 (0.833 to 0.882) n=1110 | 0.926 (0.916 to 0.936) n=11 643 | 0.920 (0.911 to 0.930) n=12 753 | ||
NPV, negative predictive value; PCC, proportion correctly classified; PPV, positive predictive value; ROC, receiver operating characteristic; Sn, sensitivity; Sp, specificity.