Table 3

Risk of hip fracture for patients with stroke according to the duration of thiazide use

Duration of thiazide usePatients (n)Hip fracturesPerson- yearsIncidence rate*Univariate modelMultivariate model†
Crude HR (95% CI)p ValueAdjusted HR (95% CI)p Value
Non-user3735926596.413.91 (ref)1 (ref)
1–90 days1488282710.110.30.76 (0.50 to 1.16)0.2060.73 (0.48 to 1.13)0.160
91–365 days1296222477.58.90.69 (0.43 to 1.09)0.1110.69 (0.43 to 1.11)0.127
>365 days951101887.35.30.42 (0.22 to 0.81)0.0100.41 (0.22 to 0.79)0.008
  • *Per 1000 person-years.

  • †Multivariate Cox proportional hazard regression model, adjusting for all baseline characteristics (listed in table 1) and competing mortality.