Table 4

ORs for CKD progression by baseline levels of FGF23, PTH and vitamin D

VariableUnivariateMultivariable (corrected for age, eGFR, gender and uACR) 
OR (95% CI)OR (95% CI)p value
Vitamin D (nmol/L)
 <251.86 (1.01 to 3.41)*1.49 (0.79 to 2.82)NS
 26–501.39 (0.97 to 1.98)1.26 (0.87 to 1.84)NS
 51–751.17 (0.81 to 1.69)1.19 (0.81 to 1.75)NS
 >751 (Ref)1 (Ref)
FGF 23 (pg/mL)
 <251 (Ref)1 (Ref)
 25–511.42 (0.77 to 2.45)1.22 (0.64 to 2.32)NS
 52–702.07 (1.07 to 4.02)*1.38 (0.69 to 2.77)NS
 >702.27 (1.09 to 4.75)*1.27 (0.58 to 2.78)NS
PTH (pg/mL)
 <351 (Ref)1 (Ref)
 35–651.75 (1.24 to 2.45)*1.54 (1.08 to 2.20)0.016
 66–952.14 (1.39 to 3.28)*1.58 (1.00 to 2.48)0.049
 >952.59 (1.48 to 4.53)*1.44 (0.79 to 2.62)NS
  • CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; FGF, fibroblast growth factor; NS, not significant; PTH, parathyroid hormone; uACR, urinary albumin to creatinine ratio.