Patients receiving at least one drug for condition  treatmentTotal medications prescribed MINUS hypoglycaemic drugs‡, mean±SDp Value (t-test)
(B) Intensity of condition-specific treatment and general polypharmacy
 Overtreated diabetes, n=1311.0±3.70.01
 Treated diabetes, n=127.2±3.1
Total medications prescribed MINUS hypotensive drugs§, mean±SD
 Overtreated hypertension, n=508.4±3.80.285
 Treated hypertension, n=607.7±2.9
  • *Overtreated diabetes=having a diagnosis of diabetes, taking at least one hypoglycaemic medication and having a glycosylated haemoglobin ≤7.5%.23

  • †Overtreated hypertension=having a diagnosis of hypertension, a systolic blood pressure ≤128 and hypertension medications ≥1.16

  • ‡Where hypoglycaemic drugs=biguanides (metformin), sulfonylureas, alpha-glucosidase inhibitors, any insulin and/or dipeptidyl peptidase-4.

  • §Where hypotensive drugs=angiotensin converting enzyme inhibitors, calcium channel blockers, diuretics, β-blockers, angiotensin II type 1 receptor antagonists and α-adrenergic blocking agents, older agents including: methyldopa, reserpine and hydralazine were not found to be used in this cohort.