Table 3

Incidence rate (/100 000 women years) of cervical intraepithelial neoplasia grade three and invasive cancer (CIN3+) in cluster-randomised cohorts of 16- to 17-year-old HPV-16/18 vaccine recipients, and unvaccinated originally 18- to 19 year old women. Passive follow- up was by the population-based Finnish Cancer Registry up to 10 years post vaccination.

End point of the follow-upVaccineControl
Person yrsnRate*NPerson yrsnRate*
FCR registered CIN3+ diagnoses
 Active2472    10 19915 665  62 628
 Intermittent2 466   1 23218115 6347 815
 Passive2 465  12 56143215 627   85 3287993
KI re-reviewed CIN3+ diagnoses
 Intermittent2 466   1 23218115 634  7 815
 Passive2 465   12 56132415 627   85 3285059
  • Active (0–4 years), Intermittent (4–4.5 years), Passive (4.5–10 years)

  • *incidence/100 000 women years