Comparison between newborns of metal load between subgroups according to the mothers ‘proximal exposure’. The metal load in newborns of different subgroups were compared with each other. Analysis was by multiple quantile regression on median values as linear function of the independent variable, ‘proximal exposure’. For ease in reading the data, the colour yellow indicates that the group in the column on the left in each panel has significantly higher load (p<0.05) than the one in the column on the right in the same panel. If vice versa, the line is enhanced in green colour. Panel A compares exposure subgroups 1 with 3; panel B compares exposure subgroups 1 with 2+3
Newborn | ||||||||
A | ||||||||
Metal | Median exposure 1 | 95% CI | Median exposure 3 | 95% CI | Difference | p>|t| | 95% CI - INF | 95% CI -SUP |
Al | 4.55 | 3.85 to5.25 | 5.71 | 4.79 to6.63 | −1.16 | 0.049 | −2.31712 | −0.0028796 |
Fe | 26.83 | 23.32 to 30.34 | 31.82 | 27.2 to36.44 | −4.99 | 0.092 | −10.78903 | 0.8090262 |
Mg | 153 | 145.02 to 160.98 | 157 | 146.5 to167.5 | -4 | 0.551 | −17.1852 | 9.185197 |
Mn | 0.3 | 0.25 to 0.35 | 0.3 | 0.24 to0.36 | 0 | 1 | −0.0769879 | 0.0769879 |
Ba | 0.4 | 0.35 to 0.45 | 0.36 | 0.3 to0.42 | 0.04 | 0.326 | −0.0400217 | 0.1200217 |
As | 0.011 | 0.01 to 0.01 | 0.011 | 0.01 to0.01 | 0 | 1 | −0.0019135 |
0.001913 −0.0019135 0.0019135 5 |
Cd | 0.0056 | 0 to 0.01 | 0.0053 | 0 to 0.01 | 0.0003 | 0.737 | −0.0014518 | 0.0020518 |
Co | 0.02 | 0.02 | 0 | |||||
Cr | 0.12 | 0.1 to0.14 | 0.13 | 0.1 to 0.16 | −0.01 | 0.558 | −0.0435074 | 0.0235074 |
Cu | 7.31 | 7.02 to 7.6 | 7.87 | 7.49 to 8.25 | −0.5599999 | 0.023 | −1.042013 | −0.0779871 |
Hg | 0.0618 | 0.05 to 0.07 | 0.0544 | 0.04 to0.06 | 0.0074 | 0.258 | −0.0054336 | 0.0202336 |
Ni | 0.19 | 0.16 to 0.22 | 0.18 | 0.14 to 0.22 | 0.01 | 0.691 | −0.0393955 | 0.0593955 |
Pb | 0.2 | 0.17 to 0.23 | 0.22 | 0.17 to0.27 | −0.02 | 0.499 | −0.0780727 | 0.0380728 |
Sr | 2.82 | 2.61 to 3.03 | 3.05 | 2.78 to3.32 | −0.23 | 0.185 | −0.5706677 | 0.1106676 |
Ti | 0.24 | 0.2 to 0.28 | 0.25 | 0.19 to0.31 | −0.01 | 0.78 | −0.080361 | 0.060361 |
U | 0.0014 | 0 to 0 | 0.0014 | 0 to0 | 0 | 1 | −0.00055 | 0.00055 |
V | 0.01 | 0.01 to 0.01 | 0.012 | 0.01 to0.01 | −0.002 | 0.189 | −0.0049906 | 0.0009906 |
W | 0.04 | 0.03 to 0.05 | 0.04 | 0.03 to 0.05 | 0 | 1 | −0.0115052 | 0.0115052 |
Zn | 201.73 | 194.33 to 209.13 | 205.68 | 195.92 to 215.44 | −3.949997 | 0.526 | −16.19486 | 8.294866 |
B | ||||||||
Metal | Median exposure 1 | 95% CI | Median exposures 2+3 | 95% CI | Difference | p>|t| | 95% CI - INF | 95% CI -SUP |
Al | 4.55 | 3.81 to 5.29 | 5.98 | 5.14 to 6.82 | −1.43 | 0.012 | −2.549591 | −0.3104087 |
Fe | 26.83 | 23.01 to 30.65 | 33.11 | 28.83 to 37.39 | −6.280001 | 0.032 | −12.01936 | −0.54064 |
Mg | 153 | 144.43 to 161.57 | 165 | 155.39 to 174.61 | −12 | 0.068 | −24.87731 | 0.8773066 |
Mn | 0.3 | 0.24 to 0.36 | 0.35 | 0.29 to 0.41 | −0.05 | 0.242 | −0.1338956 | 0.0338956 |
Ba | 0.4 | 0.34 to 0.46 | 0.43 | 0.37 to0.49 | −0.03 | 0.494 | −0.116016 | 0.056016 |
As | 0.011 | 0.01 to 0.012 | 0.012 | 0.01 to0.014 | −0.001 | 0.356 | −0.0031258 | 0.0011258 |
Cd | 0.0056 | 0.004 to 0.007 | 0.0065 | 0.005 to 0.008 | −0.0009 | 0.337 | −0.0027383 | 0.0009383 |
Co | 0.02 | 0.02 | 0 | |||||
Cr | 0.12 | 0.1 to 0.14 | 0.14 | 0.11 to 0.17 | −0.02 | 0.247 | −0.0539088 | 0.0139088 |
Cu | 7.31 | 7.01 to 7.61 | 7.97 | 7.63 to 8.31 | −0.6599998 | 0.004 | −1.109277 | −0.2107228 |
Hg | 0.0618 | 0.05 to 0.07 | 0.052 | 0.04 to 0.06 | 0.0098 | 0.105 | −0.002061 | 0.021661 |
Ni | 0.19 | 0.16 to 0.22 | 0.21 | 0.17 to0.25 | −0.02 | 0.444 | −0.0712762 | 0.0312762 |
Pb | 0.2 | 0.16 to 0.24 | 0.26 | 0.22 to0.3 | −0.06 | 0.03 | −0.1143081 | −0.0056919 |
Sr | 2.82 | 2.61 to 3.03 | 3.33 | 3.1 to3.56 | −0.51 | 0.001 | −0.8236846 | −0.1963154 |
Ti | 0.24 | 0.19 to 0.29 | 0.29 | 0.24– to 0.34 | −0.05 | 0.156 | −0.1190668 | 0.0190668 |
U | 0.0014 | 0.001 to 0.002 | 0.0019 | 0.001 to0.002 | −0.0005 | 0.067 | −0.0010348 | 0.0000348 |
V | 0.01 | 0.008 to 0.012 | 0.013 | 0.011 to 0.015 | −0.003 | 0.037 | −0.0058153 | −0.0001847 |
W | 0.04 | 0.03 to 0.05 | 0.05 | 0.04 to 0.06 | −0.01 | 0.21 | −0.0256367 | 0.0056367 |
Zn | 201.73 | 194.37 to 209.09 | 210.16 | 201.89 to218.43 | −8.430008 | 0.135 | −19.50161 | 2.641593 |
*Al, aluminium; Fe, iron; Mg, magnesium; Mn, manganese; Ba, barium; As, arsenic; Cd, cadmium; Co, cobalt; Cr, chromium; Cs, cesium; Cu, copper; Hg, mercury; Ni, nickel; Pb, lead; Sr, strontium; Ti, titanium; U, uranium; V, vanadium; W, tungsten; Zn, zinc.