MRI protocol
| Sequence | Scan time (min:sec) | Resolution (mm3) | Slices | FOV (cm) | TR (ms) | TE (ms) | Other parameters |
| Resting state fMRI (ss-EPI) | 8:10 | 3.6×3.6×3.6 | 36 | 23 | 2000 | 30 | 241 measurements |
| GRE | 0:34/0:36 | 0.9×0.9×3.5/0.9×0.9×3.6 | 36 | 23×17.2/23 | 300/450 | 3.2/5.7 | Flip angle 30 |
| ASL (3D) | 5:01 | 3.5×3.5×3.5/1.9×1.9×3.5 | 34 | 23/24 | 4600/4845 | 15.6/10.1 | FAIR QII, bolus 700 ms, TI 1990/2025 ms, 4/2 average/ 4/1 average |
| DTI | 7:08/7:12×2 | 2.2×2.2×2.2 | 57 | 22/24.2 | 6300/12 000 | 55/98 | 5/10 b0, 30 directions b900, 30 directions b2000 |
| 3D T1 (MP-RAGE/ FSPGR BRAVO) | 4:57/5:28 | 0.8×0.8×0.8 | 192 | 25.6/24 | 1880/8.25 | 2.9/3.16 | Flip angle 10, TI 948/600 ms, sagittal/axial |
| QSM (R2Star/3D SPGR) | 5:16/5:07 | 1.0×1.0×2.0/0.94×0.94×1.9 | 80 | 24 | 42/44.8 | 3.8–36.8/4.1–37.9 | 7/8 echoes, flip angle 17/15 |
| FLAIR | 3:09/2:45 | 0.9×0.9×5.0 | 30 | 22×16.5/22 | 8500/15 000 | 85/100 | TI 2439/2500 ms |
| Spectroscopy (PRESS) | 3:22/4:00 | 20×20×20 | – | – | 2000 | 30 | 96 averages+8 unsuppressed water scans, voxel centred in left dorsolateral prefrontal cortex |
Representative GE and Siemens parameters at the Alberta sites; parameters are shared across Siemens and GE unless otherwise indicated with two parameters listed as Siemens/GE.
ASL , arterial spin labelling; BRAVO, BRAin VOlume Imaging; DTI , diffusion tensor imaging; EPI , echo planar imaging; FAIR, flow-sensitive alternating recovery; FLAIR , fluid-attenuated inversion recovery; fMRI, functional MRI; FOV, field of view; FSPGR , fast spoiled gradient; MP RAGE, magnetisation prepared rapid acquisition gradient echo; PRESS, Point RESolved Spectroscopy; QII, quantitative imaging of perfusionusing a single subtraction II; QSM, quantitative susceptibility mapping; R2Star/3D, relaxation rate 1/T2* three-dimension; SPGR , spoiled gradient; ss-EPI, single-shot echo planar imaging; TE, echo time; TR, repetition time.