Table 3

The association of 25(OH)D level with all-cause mortality in different models (n=6377)

Number of subjects/deathTime at risk (PY)Rate (1000 PY)Model 1Model 2Model 3Model 4
HR95% CIHR95% CIHR95% CIHR95% CI
25(OH)D level quartiles (nmol/L)
 First (<34.5)1610/41826 35815.91.32(1.14 to 1.53)1.30(1.11 to 1.51)1.27(1.09 to 1.48)1.30(1.11 to 1.51)
 Second (34.5–45.1)1580/38426 29114.61.18(1.02 to 1.36)0.97(0.83 to 1.13)0.94(0.81 to 1.09)0.97(0.84 to 1.13)
 Third (45.2–58.0)1603/38627 04414.31.12(0.97 to 1.29)1.08(0.94 to 1.25)1.06(0.92 to 1.23)1.09(0.94 to 1.26)
 Fourth (≥58.1)1584/35126 87613.11.001.001.001.00
25(OH)D level (nmol/L)
 <25.0479/122779715.61.31(1.07 to 1.60)1.45(1.18 to 1.78)1.41(1.14 to 1.74)1.46(1.18 to 1.80)
 25.0–49.93340/84555 32415.31.23(1.09 to 1.37)1.07(0.95 to 1.20)1.05(0.93 to 1.17)1.07(0.96 to 1.21)
 50.0–74.92128/47236 17813.01.001.001.001.00
 ≥75.0430/100727013.81.04(0.84 to 1.29)1.08(0.87 to 1.35)1.08(0.86 to 1.34)1.08(0.87 to 1.34)
  • Model 1 adjusted for season of blood draw; model 2 adjusted for age, sex, body mass index, smoking, alcohol consumption, physical activity, education and economic difficulties in addition to model 1; model 3 adjusted for chronic illness (first definition) at baseline in addition to model 2; model 4 adjusted for chronic illness (second definition) at baseline in addition to model 2.

  • 25(OH)D, 25-hydroxyvitamin D; PY, person-years.