CAA | Control | Model 1* | Model 2b | Model 3c | ||
Variable | (n=719) | (n=7190) | Crude OR | Adjusted OR | Adjusted OR | Adjusted OR |
Demographics† | ||||||
Age | 62.57 (13.91) | 62.57 (13.92) | - | - | - | - |
Male sex | 488 (67.9) | 4880 (67.9) | - | - | - | - |
Urbanisation | ||||||
Rural | 191 (26.6) | 1964 (27.3) | 1 | 1 | 1 | 1 |
Urbanised | 528 (73.4) | 5226 (72.7) | 1.04 (0.87–1.24) | 0.95 (0.79–1.15) | 1.02 (0.85–1.22) | 0.95 (0.78–1.15) |
Income group‡ | ||||||
Low | 635 (88.3) | 6441 (89.6) | 1 | 1 | 1 | 1 |
High | 84 (11.7) | 749 (10.4) | 1.15 (0.90–1.47) | 0.93 (0.70–1.23) | 1.14 (0.89–1.46) | 0.92 (0.69–1.21) |
Risk factors | ||||||
Coronary atherosclerosis | 244 (33.9) | 354 (4.9) | 10.82 (8.85–13.24)§ | 7.97 (6.46–9.84)§ | 8.00 (6.47–9.90)§ | |
Hypertension | 459 (63.8) | 2836 (39.4) | 3.19 (2.68–3.80)§ | 2.09 (1.73–2.53)‡ | 2.12 (1.75–2.58)§ | |
Dyslipidaemia | 289 (40.2) | 1126 (15.7) | 3.77 (3.19–4.45)§ | 2.48 (2.06–2.99)‡ | 2.60 (2.15–3.14)§ | |
Diabetes mellitus | 188 (26.1) | 1457 (20.3) | 1.51 (1.26–1.80)§ | 1.51 (1.26–1.81)§ | 0.82 (0.67–1.00) | |
Cerebrovascular disease | 74 (10.3) | 710 (9.9) | 1.05 (0.81–1.36) | 1.02 (0.78–1.32) | 0.90 (0.68–1.20) | |
Peripheral vascular disease | 4 (0.6) | 59 (0.8) | 0.68 (0.25–1.87) | 0.66 (0.24–1.82) | 0.47 (0.15–1.44) | |
Varicose vein | 2 (0.3) | 47 (0.7) | 0.43 (0.10–1.75) | 0.46 (0.11–1.91) | 0.41 (0.09–1.90) | |
Aortic dissection | 4 (0.6) | 6 (0.1) | 6.67 (1.88–23.62)§ | 6.76 (1.89–24.14)§ | 3.78 (0.77–18.49) | |
Aortic aneurysm | 6 (0.8) | 9 (0.1) | 6.67 (2.37–18.73)§ | 5.82 (2.02–16.83)§ | 3.96 (1.19–13.20)§ | |
Systemic lupus erythematosus | 5 (0.7) | 10 (0.1) | 5.00 (1.71–14.63)§ | 4.09 (1.32–12.62)§ | 3.26 (0.94–11.28) | |
Rheumatoid arthritis | 9 (1.3) | 48 (0.7) | 1.89 (0.92–3.86) | 1.80 (0.87–3.73) | 1.40 (0.60–3.25) | |
Inflammatory bowel disease | 1 (0.1) | 31 (0.4) | 0.32 (0.04–2.36) | 0.35 (0.05–2.54) | 0.49 (0.07–3.67) |
*Demographics and traditional cardiovascular risk factors; bdemographics and related risk factors, excluding traditional cardiovascular risk factors; call covariates.
†Age and gender for matching were not analysed in models. Different covariates were analysed in the three models:
‡Income group was defined by the individual average monthly income during a 1 year period before the index date, and classified as low (<NTD$20 000) and high (≥ NT$20 000).
§p< 0.05.