Table 6

Preliminary synthesis for the primary outcome measures at baseline and after intervention: physical function and mobility comparing the combined intervention programme with usual care

CategoryOutcome measureAssessment point (months)StudyIntervention groupControl group
M0 (SD0)N0M1 (SD1)N1M0 (SD0)N0M1 (SD1)N1
Body weightBody weight
(kg)
18Messier et al, 20044592 (1.7)7686.8 (N/A)5896 (1.8)7894.9 (N/A)67
Physical functionPhysical function (WOMAC)6Messier et al, 20044523.6 (12.2)7617.9* (N/A)6326 (11.4)7822.4* (N/A)70
Physical function (WOMAC)18Messier et al, 20044523.6 (12.2)7629.3* (N/A)5826 (11.4)7829.4 (N/A)67
Mobility6 min walk test
(m)
6Messier et al, 200445416.2 (98.7)76482.3 (100)63434.6 (96.4)78429 (108)70
6 min walk test
(m)
18Messier et al, 200445416.2 (98.7)76477.8 (99.7)58434.6 (96.4)78429.9 (104.7)67
6 min walk test
(m)
18Focht et al, 200547414.5 (85.3)N/A465 (96.3)N/A433.4 (81.9)N/A430 (79.5)N/A
Stair climb
(s)
6Messier et al, 20044510.9 (5.8)768.8 (6.2)639.5 (5.6)789.9 (6.3)70
Stair climb
(s)
18Focht et al, 20054710.4 (7.3)N/A8.9 (5.4)NA9.4 (4.9)N/A9.9 (5.6)N/A
  • *Estimated value from figure 2 in ref. 45.

  • M0 (SD0), mean and SD at baseline; N0, participants number at baseline; M1 (SD1), mean and SD after intervention; N1, participants number after intervention; N/A, data not available.