Type of event | Training cohort (1) | Validating cohort (2) | International cohort (3) | p Values* | |||
N (%) | AUC (95% CI) | N (%) | AUC (95% CI) | N (%) | AUC (95% CI) | ||
Minor | 136 (60.4) | 0.76 (0.68 to 0.84) | 104 (50.2) | 0.73 (0.62 to 0.83) | 95 (60.9) | 0.75 (0.60 to 0.90) | 0.88 |
Major | 89 (39.6) | 0.93 (0.88 to 0.98) | 105 (49.8) | 0.81 (0.70 to 0.91) | 148 (39.1) | 0.89 (0.83 to 0.94) | 0.09 |
p Values† | 0.0006 | 0.12 | 0.06 | ||||
Focal | 76 (33.8) | 0.90 (0.83 to 0.97) | 83 (39.7) | 0.80 (0.69 to 0.92) | 109 (44.9) | 0.89 (0.84 to 0.96) | 0.31 |
Diffuse | 149 (66.2) | 0.81 (0.76 to 0.88) | 122 (60.3) | 0.79 (0.70 to 0.87) | 134 (55.1) | 0.83 (0.74 to 0.92) | 0.78 |
p Values† | 0.10 | 0.54 | 0.11 | ||||
Ischaemic | 38 (16.7) | 0.87 (0.75 to 0.98) | 28 (13.4) | 0.82 (0.62 to 1.00) | 33 (13.6) | 0.85 (0.69 to 1.00) | 0.92 |
Non-ischaemic/ inflammatory | 187 (83.3) | 0.84 (0.78 to 0.89) | 181 (86.6) | 0.82 (0.76 to 0.88) | 210 (86.4) | 0.89 (0.84 to 0.94) | 0.14 |
p Values† | 0.65 | 0.99 | 0.59 | ||||
Central | 200 (88.9) | 0.85 (0.81 to 0.90) | 192 (91.9) | 0.81 (0.75 to 0.87) | 202 (83.1) | 0.89 (0.84 to 0.94) | 0.16 |
Peripheral | 25 (11.1) | Not applicable | 17 (8.1) | 0.89 (0.74 to 1.00) | 41 (16.9) | 0.88 (0.76 to 0.98) | 0.83 |
p Values† | - | 0.27 | 0.87 |
*p Values intercohorts comparison between the AUC calculated for the different type of the event.
†p Values intracohort comparison between the AUC calculated for the different type of the event.
AUC, area under curve; NP, neuropsychiatric.