Table 2

Mean cost changes from baseline to post-treatment for ICBT and waitlist (US$).

BaselinePreintervention to postintervention
ICBTWaitlistICBTWaitlistCost difference
ICBT versus waitlist*
Mean95% CIMean95% CIMean change95% CIMean change95% CIMean difference95% CI
ICBT intervention costsClinician time and platform maintenance----196.66196.33 to 196.9800196.66196.33 to 196.98
Other societal costsHealthcare use425.66237.08 to 614.25323.63190.75 to 456.50−71.21−79.86 to −62.5890.9984.42 to 97.57−162.21−173.32 to −151.32
Medicines32.2013.77 to 51.5818.660–38.28−28.88−29.74 to −28.01−15.80−16.64 to −14.97−13.07−14.27 to −11.88
Total healthcare costs457.86261.30 to –654.42342.29208.78 to 475.7996.5787.56 to 105.5675.1968.56 to 81.8220.579.78 to 31.36
Supportive resources48.09−0.97 to 98.1116.24−0.52 to 33.0178.5275.97 to 81.06132.77131.39 to 134.15−54.25−57.13 to −51.37
Prescription- free drugs and supplements19.06−11.72 to 50.808.971.41 to 16.50−32.47−33.83 to −31.11−6.62−6.96 to 6.28−25.85−27.26 to −24.45
School absence129.4725.34 to 233.60 70.02 36.29 to 103.7756.8252.09 to 61.55101.2599.02 to 103.48−44.43−49.65 to −39.06
Academic production loss43.878.46 to 79.2832.74−4.88 to 70.3783.0480.83 to 85.25125.13123.01 to 127.25−42.09−45.12 to −39.21
Total societal costs698.36421.51 to 975.21470.26317.41 to 623.11282.74270.30 to 295.17427.72419.57 to 435.86−144.98−159.79 to −130.16
Health outcomesNumber of treatment responders (%)----27%20% to 35%0%0%27%20% to 35%
QALYs0.950.95 -0.960.960.95 -0.97−0.0015†−0.005 to −0.0025−0.00075−0.005 to -0. 0025−0.00065−0.00073 to −0.00056
VAS66.1158.60 to 73.6166.2058.80 to 73.590.0007†−0.0168 to 0.0181−0.0034−0.0169 to 0.01040.00410.0034 to 0.0049
  • *Negative values indicating cost-savings of ICBT compared with waitlist.

  • Values have been multiplied with the adjustment factor of the intervention period of 3 months/1 year that is, 0.25.

  • ICBT, internet-delivered cognitive behaviour therapy; QALY, quality-adjusted life year; VAS, visual analogue scale.