CIs RSE cumulative probability to observe at least one AEI by week associated with a probability of occurrence of event of 1%
| Week | Expected population medically followed by the enrolled practices | Cumulative vaccine coverage after 14 weeks (%) | Cumulative no of vaccinated subjects | Cumulative no of subjects reported ≥1 AEIs | Average proportion of AEI reported (%) | Lower 95% CL (%) | Upper 95% CL (%) | Cumulative probability to observe at least one event (%) | Associated RSE (%) |
| 1 | 50 000 | 20 | 714 | 7 | 1.00 | 0.4 | 2.0 | 99.37 | 37.2 |
| 2 | 50 000 | 20 | 1 428 | 14 | 1.00 | 0.5 | 1.6 | 100.00 | 26.3 |
| 3 | 50 000 | 20 | 2 142 | 21 | 1.00 | 0.6 | 1.5 | 100.00 | 21.5 |
| 4 | 50 000 | 20 | 2 857 | 28 | 1.00 | 0.7 | 1.4 | 100.00 | 18.6 |
| 5 | 50 000 | 20 | 3 571 | 35 | 1.00 | 0.7 | 1.4 | 100.00 | 16.7 |
| 6 | 50 000 | 20 | 4 285 | 42 | 1.00 | 0.7 | 1.3 | 100.00 | 15.2 |
| 7 | 50 000 | 20 | 5 000 | 50 | 1.00 | 0.7 | 1.3 | 100.00 | 14.1 |
| 8 | 50 000 | 20 | 5 714 | 57 | 1.00 | 0.8 | 1.3 | 100.00 | 13.2 |
| 9 | 50 000 | 20 | 6 428 | 64 | 1.00 | 0.8 | 1.3 | 100.00 | 12.4 |
| 10 | 50 000 | 20 | 7 142 | 71 | 1.00 | 0.8 | 1.3 | 100.00 | 11.8 |
| 11 | 50 000 | 20 | 7 857 | 78 | 1.00 | 0.8 | 1.2 | 100.00 | 11.2 |
| 12 | 50 000 | 20 | 8 571 | 85 | 1.00 | 0.8 | 1.2 | 100.00 | 10.7 |
| 13 | 50 000 | 20 | 9 285 | 92 | 1.00 | 0.8 | 1.2 | 100.00 | 10.3 |
| 14 | 50 000 | 20 | 10 000 | 100 | 1.00 | 0.8 | 1.2 | 100.00 | 9.9 |
| 1 | 50 000 | 10 | 357 | 3 | 1.00 | 0.2 | 2.4 | 87.26 | 52.7 |
| 2 | 50 000 | 10 | 714 | 7 | 1.00 | 0.4 | 2.0 | 99.37 | 37.2 |
| 3 | 50 000 | 10 | 1 071 | 10 | 1.00 | 0.4 | 1.7 | 99.98 | 30.4 |
| 4 | 50 000 | 10 | 1 428 | 14 | 1.00 | 0.5 | 1.6 | 10000 | 26.3 |
| 5 | 50 000 | 10 | 1 785 | 17 | 1.00 | 0.6 | 1.5 | 100.00 | 23.6 |
| 6 | 50 000 | 10 | 2 142 | 21 | 1.00 | 0.6 | 1.5 | 100.00 | 21.5 |
| 7 | 50 000 | 10 | 2 500 | 25 | 1.00 | 0.6 | 1.5 | 100.00 | 19.9 |
| 8 | 50 000 | 10 | 2 857 | 28 | 1.00 | 0.7 | 1.4 | 100.00 | 18.6 |
| 9 | 50 000 | 10 | 3 214 | 32 | 1.00 | 0.7 | 1.4 | 100.00 | 17.6 |
| 10 | 50 000 | 10 | 3 571 | 35 | 1.00 | 0.7 | 1.4 | 100.00 | 16.7 |
| 11 | 50 000 | 10 | 3 928 | 39 | 1.00 | 0.7 | 1.4 | 100.00 | 15.9 |
| 12 | 50 000 | 10 | 4 285 | 42 | 1.00 | 0.7 | 1.3 | 100.00 | 15.2 |
| 13 | 50 000 | 10 | 4 642 | 46 | 1.00 | 0.7 | 1.3 | 100.00 | 14.6 |
| 14 | 50 000 | 10 | 5 000 | 50 | 1.00 | 0.7 | 1.3 | 100.00 | 14.1 |
| 1 | 50 000 | 5 | 178 | 1 | 1.00 | 0.0 | 3.1 | 53.24 | 74.6 |
| 2 | 50 000 | 5 | 357 | 3 | 1.00 | 0.2 | 2.4 | 87.26 | 52.7 |
| 3 | 50 000 | 5 | 535 | 5 | 1.00 | 0.3 | 2.2 | 97.04 | 43.0 |
| 4 | 50 000 | 5 | 714 | 7 | 1.00 | 0.4 | 2.0 | 99.37 | 37.2 |
| 5 | 50 000 | 5 | 892 | 8 | 1.00 | 0.4 | 1.8 | 99.87 | 33.3 |
| 6 | 50 000 | 5 | 1 071 | 10 | 1.00 | 0.4 | 1.7 | 99.98 | 30.4 |
| 7 | 50 000 | 5 | 1 250 | 12 | 1.00 | 0.5 | 1.7 | 100.00 | 28.1 |
| 8 | 50 000 | 5 | 1 428 | 14 | 1.00 | 0.5 | 1.6 | 100.00 | 26.3 |
| 9 | 50 000 | 5 | 1 607 | 16 | 1.00 | 0.6 | 1.6 | 100.00 | 24.8 |
| 10 | 50 000 | 5 | 1 785 | 17 | 1.00 | 0.6 | 1.5 | 100.00 | 23.6 |
| 11 | 50 000 | 5 | 1 964 | 19 | 1.00 | 0.6 | 1.5 | 100.00 | 22.5 |
| 12 | 50 000 | 5 | 2 142 | 21 | 1.00 | 0.6 | 1.5 | 100.00 | 21.5 |
| 13 | 50 000 | 5 | 2 321 | 23 | 1.00 | 0.6 | 1.5 | 100.00 | 20.7 |
| 14 | 50 000 | 5 | 2 500 | 25 | 1.00 | 0.6 | 1.5 | 100.00 | 19.9 |
AEI, adverse event of interest; RSE, relative SE.