Patient characteristics that are expected to predict outcome (prognostic), or that are expected to interact with treatment (predictive)
Per cent of data complete in MR CLEAN | Prognostic | Predictive | |
---|---|---|---|
Clinical | |||
Age6 15 | 100% | x | |
Baseline NIHSS16 17 | 100% | x | |
History of diabetes mellitus18 | 100% | x | |
History of previous stroke19 | 100% | x | |
History of atrial fibrillation20 | 100% | x | |
Prestroke mRS score19 | 100% | x | |
Systolic blood pressure21 | 100% | x | |
IV treatment with alteplase22–24 | 100% | x | |
Time from onset stroke to groin puncture25 26 | 100%* | x | x |
Radiological | |||
ASPECTS6 27 | 99.2% | x | |
Location of intracranial occlusion on non-invasive vessel imaging28 29 | 99.8% | x | |
Collateral score on CTA29 30 | 98.4% | x | x |
*Of patients undergoing intra-arterial treatment.
ASPECTS, Alberta Stroke Program Early CT score; CTA, CT angiography; IV, intravenous; NIHSS, National Institutes of Health Stroke Scale; MR CLEAN, Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands; mRS, modified Rankin Scale.