Comparison of current review with results of two previous reviews in terms of successful recruitment to target sample size and extensions to recruitment
| Review | McDonald et al3 | Sully et al4 | This study | This study |
|---|---|---|---|---|
| Recruitment period | 1994–2002 | 2002–2008 | 2009–2016 | 2004–2016 |
| Number of trials in the study | N=122 | N=73 | N=90 | N=151 |
| Recruited 100% of original target | 38 of 122 (31%) | 40 of 73 (55%) | 45 of 90 (50%) | 61 of 151 (40%) |
| Original target was revised | 42 of 122 (34%) | 14 of 73 (19%) | 35 of 90 (39%) | 52 of 151 (34%) |
| Original target revised upward | 6 of 42 (14%) | 5 of 14 (36%) | 10 of 35 (29%) | 11 of 52 (21%) |
| Original target revised downward | 36 of 42 (86%) | 9 of 14 (64%) | 25 of 35 (71%) | 41 of 52 (79%) |
| Recruited 80% of original target | 67 of 122 (55%) | 57 of 73 (78%) | 65 of 90 (72%) | 95 of 151 (63%) |
| Recruited 100% of revised target | 19 of 42 (45%) | 10 of 14 (71%) | 26 of 35 (74%) | 28 of 52 (54%) |
| Recruited 80% of revised target | 34 of 42 (80%) | 13 of 14 (93%) | 31 of 35 (89%) | 48 of 52 (92%) |
| Extended their recruitment | 65 of 122 (54%) | 33 of 73 (45%) | 28 of 90 (31%) | 49 of 151 (32%) |