Table 1

DMT attributes and levels

Attributes	Levels	Description
Preventing relapse	2	Presenting a relapse every 2 years Presenting a relapse every 5 years
Preventing disease progression	2	Preventing the disease from getting worse/progressing for 2 years Preventing the disease from getting worse/progressing for 5 years
Side effect risk	2	Rare but severe, life-threatening side effects (including PML) Frequent but mild/moderate side effects
Route of administration	3	Oral Subcutaneous–intramuscular Intravenous
Frequency of administration	4	Daily Every 2 days—weekly Monthly Twice per year