Table 3

AUC values for each gene

MCS groupControl group
GenesMean AUC±SDMean AUC±SDp Values*Adjusted p values†
IL-1β1.3520.7051.0500.6490.2351.0
IL-60.0180.0090.0120.0060.0300.45
IL-81.1330.6871.3160.6710.3431.0
IL-100.0250.0360.0090.0040.0741.0
TNFα0.3020.1890.2600.0850.4941.0
NFKB10.8650.3210.7140.1600.1051.0
P2RX40.4550.2170.3740.1040.2061.0
P2RX50.5970.2170.5840.2900.7941.0
TRPV10.1020.0310.0950.0360.5931.0
TRPV40.0160.0190.0080.0050.1291.0
TRPA10.0100.0060.0080.0050.3851.0
ADRB21.0220.3321.0060.3300.7811.0
COMT0.3690.1810.3110.0790.2591.0
CAT6.3142.1546.5272.6190.9001.0
ASAH111.9044.2979.6572.5610.0921.0
SPHK10.1010.0660.0800.0300.2691.0
SGPL10.5980.1710.5440.1360.3501.0
  • *p Values calculated for each gene using Student's t-test.

  • †pValues after Holm-Bonferroni correction for multiple testing.

  • Values have been estimated using trapezoidal integration covering the 5-hour time span between initial and the last blood sample. AUC values are presented as group means with SD.

  • ADRB2, adrenergic β-2 receptor; ASAH1, N-acylsphingosine amidohydrolase (acid ceramidase) 1; AUC, area under the curve; CAT, catalase; COMT, catechol-O-methyltransferase; IL, interleukin; MCS, multiple chemical sensitivity; NFKB1, nuclear factor of κ light polypeptide gene enhancer in B cells 1; P2RX4, purinergic receptor P2X, ligand-gated ion channel, 4; P2RX5, purinergic receptor P2X, ligand-gated ion channel, 5; SGPL1, sphingosine-1-phosphate lyase 1; SPHK1, sphingosine kinase 1; TNF, tumour necrosis factor; TRPA1, transient receptor potential cation channel, subfamily A, member 1; TRPV1, transient receptor potential cation channel, subfamily V, member 1; TRPV4, transient receptor potential cation channel, subfamily V, member 4.