Influence of providing information communicating risk of fracture and treatment benefits
| Group 1 (n=51) | Group 2 (n=49) | Group 3 (n=51) | Group 4 (n=49) | Entire cohort | |
|---|---|---|---|---|---|
| Participant estimates at baseline | |||||
| 5-year fracture risk high enough to consider taking medications (tablet/intravenous) to prevent fracture (any/hip) (%) | |||||
| Any fracture/tablets (%) | 50 (23, 75) | 50 (28, 60) | 50 (35, 80) | 50 (20, 60) | 50 (25, 70) |
| Any fracture/intravenous (%) | 53 (40, 80) | 55 (20, 72) | 60 (50, 80) | 60 (30, 80) | 60 (30, 80) |
| Hip fracture/tablets (%) | 50 (30, 80) | 50 (35, 73) | 55 (50, 80) | 48 (20, 60) | 50 (30, 75) |
| Hip fracture/intravenous (%) | 60 (45, 80) | 55 (30, 80) | 60 (40, 80) | 65 (30, 80) | 60 (40, 80) |
| Risk of any fracture in next 5 years (%) | 25 (10, 50) | 25 (10, 50) | 20 (10, 50) | 15 (10, 40) | 20 (10, 50) |
| None/very low risk | 14 | 17 | 16 | 24 | 18 |
| Low risk | 44 | 38 | 45 | 47 | 43 |
| Moderate risk | 30 | 42 | 29 | 24 | 31 |
| High risk | 12 | 4 | 10 | 2 | 7 |
| Very high risk | 0 | 0 | 0 | 2 | 1 |
| Risk of hip fracture in next 5 years (%) | 15 (10, 50) | 20 (10, 45) | 20 (10, 40) | 10 (5, 30) | 19 (10, 40) |
| Garvan fracture risk calculator estimates | |||||
| 5-year osteoporotic fracture risk | 7.9 (5.8, 12.3) | 7.3 (4.4, 9.9) | 8.5 (5.6, 14.6) | 7.1 (5.0, 9.6) | 7.4 (5.5, 12.0) |
| 5-year hip fracture risk | 1.6 (0.8, 3.4) | 1.2 (0.7, 2.4) | 1.8 (0.8, 4.1) | 1.3 (0.6, 2.0) | 1.4 (0.8, 3.0) |
| Participant estimates after information on fracture risk and treatment benefits provided | |||||
| Risk of any fracture in next 5 years (%) | 14 (9, 30) | 19 (10, 27) | 15 (7, 30) | 10 (8, 20) | 12 (8, 30) |
| None/very low risk | 20 | 29 | 27 | 33 | 27 |
| Low risk | 45 | 47 | 47 | 47 | 47 |
| Moderate risk | 31 | 18 | 20 | 10 | 20 |
| High risk | 4 | 6 | 4 | 8 | 6 |
| Very high risk | 0 | 0 | 2 | 2 | 1 |
| Risk of hip fracture in next 5 years (%) | 8 (2, 20) | 10 (2, 20) | 10 (2, 20) | 10 (2, 15) | 10 (2, 20) |
Data are per cent or median (Q1, Q3). Group 1: framed as chance of having an event and treatment benefits in natural frequencies; group 2: framed as chance of not having an event and treatment benefits in natural frequencies; group 3: framed as chance of having an event and treatment benefits with number needed to treat; group 4: framed as chance of not having an event and treatment benefits with number needed to treat.