Table 4

ANCOVA comparing secondary outcome measures within and between group

Outcome measure by groupnAdjusted mean difference from baselineSE95% CIp Valuep Value between group
Lower limitUpper limit
Modified Ferriman-Gallwey score
 Standardised15−2.520.42−3.40−1.65<0.0010.09
 Individualised14−1.440.44−2.35−0.540.001
BMI (kg/m2)
 Standardised15−0.410.46−1.400.540.370.83
 Individualised15−0.260.48−1.250.720.59
Weight (kg)
 Standardised15−1.131.30−3.801.540.380.85
 Individualised14−0.771.34−3.531.990.57
Waist-to-hip ratio
 Standardised150.0020.01−0.020.020.840.02*
 Individualised12−0.040.01−0.06−0.01<0.001
Waist circumference (cm)
 Standardised15−0.801.28−3.451.850.530.27
 Individualised14−2.961.38−5.81−0.110.03
MYMOP1
 Standardised172.04†0.391.242.84<0.0010.98
 Individualised182.02†0.381.242.80<0.001
MYMOP2
 Standardised170.870.390.071.670.030.29
 Individualised181.460.380.682.24<0.001
MYMOP activity
 Standardised112.38†0.431.493.26<0.0010.19
 Individualised151.590.360.842.34<0.001
MYMOP well-being
 Standardised160.920.320.281.570.0040.97
 Individualised180.900.300.301.510.003
PCOSQ total
 Standardised175.171.03.097.25<0.0010.33
 Individualised183.741.001.725.77<0.001
PCOSQ emotions
 Standardised170.97†0.220.531.42<0.0010.77
 Individualised181.06†0.210.631.49<0.001
PCOSQ body hair
 Standardised170.840.260.311.380.0010.16
 Individualised180.320.26−0.200.830.11
PCOSQ weight
 Standardised170.790.320.151.440.010.61
 Individualised180.560.31−0.061.190.07
PCOSQ infertility
 Standardised171.17†0.250.661.68<0.0010.26
 Individualised180.770.240.271.270.001
PCOSQ menstrual
 Standardised171.40†0.240.911.88<0.0010.28
 Individualised181.03†0.230.561.50<0.001
DLQI
 Standardised16−1.970.66−3.32−0.620.0030.09
 Individualised18−0.360.62−1.630.910.56
  • *Favouring individualised CHM.

  • †Achieved MCID.

  • BMI, body mass index; DLQI, Dermatology Life Quality Index; MCID, minimum clinically important difference; MYMOP, Measure Yourself Medical Outcome Profile; PCOSQ, Polycystic Ovary Syndrome Questionnaire.