Summary characteristics of the 39 included studies
| Global N=39 | Studies with published results n=26 | Studies in progress n=13 | |||||
|---|---|---|---|---|---|---|---|
| Number | (%) | NR | Number | (%) | Number | (%) | |
| Study diffusion | |||||||
| Registry database only | 8 | (20) | 0 | (0) | 8 | (61) | |
| Journals | 31 | (79) | 26 | (100) | 5 | (38) | |
| Specialist medical journals | 16 | (51) | 15 | (58) | 1 | (3) | |
| Paediatric and adolescent medical journals | 12 | (39) | 10 | (38) | 2 | (5) | |
| General medical journals | 3 | (10) | 1 | (4) | 2 | (5) | |
| Eligible diseases | |||||||
| Unique | 32 | (82) | 23 | (88) | 9 | (69) | |
| Set of conditions | 7 | (18) | 3 | (12) | 4 | (31) | |
| Time of intervention | 1 | ||||||
| Before the last paediatric consultation | 26 | (68) | 17 | (65) | 9 | (69) | |
| Between the last paediatric and the first adult consultation | 11 | (29) | 9 | (35) | 2 | (15) | |
| After the first adult consultation | 1 | (3) | 0 | (0) | 1 | (8) | |
| Data collection of interventional group | 1 | ||||||
| Retrospective | 14 | (36) | 13 | (50) | 1 | (8) | |
| Prospective | 25 | (64) | 13 | (50) | 11 | (85) | |
| Number of comparison groups by study | |||||||
| 0 (precomparison/postcomparison in a single group) | 9 | (23) | 7 | (27) | 2 | (15) | |
| 1 | 25 | (64) | 16 | (61) | 9 | (69) | |
| >1 | 5 | (13) | 3 | (11) | 2 | (15) | |
| Type of comparison group (n=30)* | |||||||
| Historical group | 11 | (37) | 10 | (38) | 1 | (9) | |
| Randomised group | 9 | (30) | 1 | (4) | 8 | (73) | |
| Non-participants group | 5 | (17) | 5 | (19) | 0 | (0) | |
| Contemporary data from another service/center/care setting | 5 | (17) | 3 | (11) | 2 | (18) | |
| Non-randomised parallel group | 1 | (3) | 0 | (0) | 1 | (9) | |
| Mixed data of historical cohort and non-participants group | 1 | (3) | 1 | (4) | 0 | (0) | |
| Blinding strategy | 2 | (5) | 0 | (0) | 2 | (15) | |
| Control in randomised studies (n=9) | |||||||
| Usual care | 6 | (67) | 1 | (4) | 5 | (62) | |
| Other intervention | 3 | (33) | 0 | (0) | 3 | (38) | |
| Median | (Minimum–maximum) | NR | Median | (Minimum–maximum) | Median | (Minimum–maximum) | |
|---|---|---|---|---|---|---|---|
| Size of intervention group or recruitment target (studies in progress) | 41 | (11–215) | 42 | (11–215) | 33 | (14–105) | |
| Number of outcomes | 4 | (1–12) | 3 | (1–7) | 6 | (1–12) | |
| Time of last data collection after transfer (months) | 12 | (3–96) | 3 | 12 | (3–96) | 12 | (3–24) |
*The fact that the sum of comparison is higher than total number of studies is explained by the possibility for studies to have more than one comparison group.
NR, not reported.