Table 3

Multivariate-adjusted HRs and 95% CIs of first CHD event, for HS versus no HS (reference category), among non-manual and manual workers only

Non-manual workersManual workers
N#CHDHR95% CIN#CHDHR95% CIp Value*
Job strain categories
All events in the entire follow-up period
No HS106732REF125837REF0.7
HS399171.700.94 to 3.08560221.941.13 to 3.32
Events occurred after the first 3 years of follow-up
No HS105827REF124734REF0.7
HS394141.680.88 to 3.23553201.951.11 to 3.43
  • MONICA Brianza, PAMELA and SEMM cohorts. Men were 25–64 years old and employed at time of recruitment.

  • HRs estimated from Cox regression models with age as the time scale, adjusted for study type (population-based vs factory-based), systolic blood pressure, total cholesterol, HDL cholesterol, diabetes and current smokers. Job strain categories are based on items of Psychological Job Demand and Decision Latitude.

  • *p Value for interaction test between occupational class and high strain (1 df Wald χ2 test).

  • CHD, coronary heart disease; HDL, high-density lipoprotein; HS, high job strain; no HS, non-high job strain; PAMELA, Pressioni Arteriose Monitorate E Loro Associazioni; SEMM, Surveillance of Employees of the Municipality of Milan.