Table 2

Multivariate-adjusted HRs and 95% CIs of first CHD event, for HS versus no HS, as reference category

Entire sampleOccupational class
 Managers and proprietorsManual and non-manual workers
N#CHDHR95% CIN#CHDHR95% CIN#CHDHR95% CIp Value*
Job strain categories
All events in the entire follow-up period included
No HS3038126REF71357REF232569REF0.04
HS1065461.390.99 to 1.9710670.710.32 to 1.56959391.781.20 to 2.66
Events occurred after the first 3 years of follow-up
No HS3002108REF69747REF230561REF0.04
HS1049391.390.96 to 2.0310250.610.24 to 1.55947341.801.17 to 2.76
  • MONICA Brianza, PAMELA and SEMM cohorts. Men were 25–64 years old and employed at time of recruitment.

  • HRs estimated from Cox regression models with age as the time scale, adjusted for study type (population-based vs factory-based), systolic blood pressure, total cholesterol, HDL cholesterol, diabetes and current smokers. Job strain categories are based on items of Psychological Job Demand and Decision Latitude.

  • *p Value for interaction test between occupational class and high-strain (1 df Wald χ2 test).

  • CHD, coronary heart disease; HDL, high-density lipoprotein; HS, high job strain; no HS, non-high job strain; PAMELA, Pressioni Arteriose Monitorate E Loro Associazioni; SEMM, Surveillance of Employees of the Municipality of Milan.