Table 2

Utility, resource use and cost parameters used in the model

ParameterMean estimateDistributionSource
HF utility score when hospitalised0.66 (0.26 SD)β (7321, 3772)*Reed et al26
HF utility score when not-hospitalised0.77 (0.23 SD)β (7978, 2383)*Reed et al26
Duration of hospitalisation (days)13.21 (0.39 SE)γ (1148.29, 0.01)*CPRD-HES3
3-monthly cost when hospitalised (age <75 years)£9104 (349.61 SE)γ (678.06, 13.43)*CPRD-HES3
3-monthly cost when not-hospitalised (age <75 years)£682 (23.72 SE)γ (827.17, 0.82)*CPRD-HES3
3-monthly cost when hospitalised (age ≥75 years)£8057 (192.77 SE)γ (1746.96, 4.61)*CPRD-HES3
3-monthly cost when not-hospitalised (age ≥75 years)£569 (14.52 SE)γ (1536.51, 0.37)*CPRD-HES3
Clinically guided unscheduled outpatient visits (24 months)1.10 (0.13 SE)γ (71.60, 0.02)*PRIMA27
BNP-guided unscheduled outpatient visits (24 months)1.40 (0.14 SE)γ (94.52, 0.02)*PRIMA27
BNP-guided additional cost of medications (18 months)£58.32 (6.20 SE)γ (88.42, 0.66)*TIME-CHF11
Unit cost of an outpatient visit£123FixedDoH28
Unit cost of a BNP test£25FixedNICE29
  • *β and γ parameters were determined using the methods of moments described elsewhere.30

  • CPRD, Clinical Practice Research Database; HES, Hospital Episode Statistics.