Multivariable logistic regression analysis predicting HDP and/or GDM
| HDP | GDM | Composite of HDP/GDM | ||||
|---|---|---|---|---|---|---|
| OR (95% CI) | aOR (95% CI) | OR (95% CI) | aOR (95% CI) | OR (95% CI) | aOR (95% CI) | |
| 4th quartile TGs at 1st trimester | 2.35 (1.30 to 4.23) | 1.94 (1.05 to 3.59)* | 2.21 (1.48 to 3.29) | 2.09 (1.37 to 3.17) | 2.28 (1.60 to 3.25) | 2.04 (1.41 to 2.95)* |
| 4th quartile TGs at 2nd trimester | 1.97 (1.12 to 3.45)* | 1.83 (1.02 to 3.27)* | 2.05 (1.38 to 3.04)* | 1.93 (1.25 to 2.98) * | 1.97 (1.39 to 2.79)* | 1.81 (1.25 to 2.63)* |
| 4th quartile TGs at 3rd trimester | 2.28 (1.32 to 3.94)* | 2.89 (1.72 to 4.84)* | 1.63 (1.09 to 2.44)* | 1.51 (0.99 to 2.28)* | 1.80 (1.27 to 2.54)* | 1.78 (1.24 to 2.54)* |
| Higher (4th quartile) TGs elevation† | 1.88 (1.06 to 3.33)* | 2.09 (1.16 to 3.78)* | 1.24 (0.82 to 1.89) | 1.26 (0.83 to 1.94) | 1.49 (1.04 to 2.13)* | 1.58 (1.09 to 2.28)* |
| 4th quartile TC at 1st trimester | 1.77 (0.97 to 3.26) | 1.69 (0.91 to 3.13) | 1.10 (0.72 to 1.68) | 1.15 (0.75 to 1.78) | 1.37 (0.95 to 1.97) | 1.38 (0.95 to 2.01) |
| 4th quartile LDL at 1st trimester | 1.72 (0.95 to 3.10) | 1.48 (0.80 to 2.71) | 1.43 (0.96 to 2.14) | 1.41 (0.93 to 2.15) | 1.56 (1.09 to 2.12)* | 1.46 (1.01 to 2.10)* |
Adjusted confounding variables included maternal age, pre-pregnancy BMI, education years, fasting glucose levels and gestational age at blood collection.
*p<0.05.
‡Adjusted before mentioned variables plus weight gain during gestation.
BMI, body mass index; GDM, gestational diabetes mellitus; HDP, hypertensive disorders of pregnancy; LDL-c, low-density lipoprotein cholesterol; TC, total cholesterol; TGs, triglycerides.