Table 3

Incidence and HRs (95% CIs) of end-stage renal disease in different subgroups according to the baseline cardiovascular health score

10–14 (n=35 810)5–9 (n=53 815)0–4 (n=1818)One score decrease (n=91 443)p Value for trendp Interaction*
Sex30 (0.43)
7.25
1.25 (0.71 to 2.20)
<0.001
 Women, case number29 (0.24) 59 (0.31)
Cumulative incidence/10002.60 3.34
 HR‡1 1.19 (1.03 to 1.39)0.017
 Men, case number48 (0.20)155(0.33)11 (0.63)214 (0.29)
 Cumulative incidence/10002.203.796.753.34
 HR‡11.59 (1.15 to 2.22)2.90 (1.48 to 5.69)1.20 (1.12 to 1.29)<0.001
Age2.203.796.753.34<0.001
 ≤60 years, case number62 (0.21)150 (0.36)11 (0.71)223 (0.31)
 Cumulative incidence/10002.354.127.703.51
 HR‡11.50 (1.10 to 2.05)2.79 (1.43 to 5.46)1.19 (1.11 to 1.28)<0.001
 >60 years, case number15 (0.22)35 (0.28)50(0.26)
 Cumulative incidence/10002.283.842.82
 HR‡11.56 (0.90 to 2.72)1.14 (0.71 to 1.87)0.11
  • *p Value for interaction between studied factors and exposure status.

  • ‡Adjusted for age (years), sex, education level (elementary school, high school or college or above), income level (income >800 RMB/month, income ≤800 RMB/month), alcohol consumption (never, past, current, <1 times/day or current, 1+ times/d), C reactive protein blood concentration (quartile 1) and estimated glomerular filtration rate.