Table 3

Incidences of obstructive sleep apnoea and RA cohort to non-RA cohort HRs of obstructive sleep apnoea

Variable	RA			Non-RA			Relative HR (95% CI)	Adjusted HR‡ (95% CI)
Variable	Event	PY	Rate†	Event	PY	Rate†	Relative HR (95% CI)	Adjusted HR‡ (95% CI)
Sex
Female	32	175 312	1.83	21	178 183	1.18	1.55 (0.89 to 2.69)	1.51 (0.87 to 2.62)
Male	35	45 223	7.74	18	46 982	3.83	2.02 (1.14 to 3.56)*	2.00 (1.13 to 3.54)*
Age, year
20–49	25	93 965	2.66	17	92 892	1.83	1.45 (0.78 to 2.68)	1.39 (0.75 to 2.58)
50–64	28	84 234	3.32	16	86 115	1.86	1.79 (0.97 to 3.30)	1.81 (0.98 to 3.36)
≥65	14	42 336	3.31	6	46 157	1.30	2.44 (0.94 to 6.34)	2.66 (1.01 to 6.97)*
Comorbidity§
No	21	118 101	1.78	15	131 128	1.14	1.55 (0.80 to 3.01)	1.58 (0.81 to 3.06)
Yes	46	102 434	4.49	24	94 037	2.55	1.76 (1.07 to 2.88)*	1.66 (1.01 to 2.73)*

*p<0.05.
†Incidence rate per 10 000 person-years.
‡Multivariable analysis including sex, age and comorbidities of hypertension, diabetes, hyperlipidemia, IHD, dysrhythmia, CHF, stroke, CKD, asthma/COPD and obesity.
§Patients with any comorbidity of hypertension, diabetes, hyperlipidaemia, IHD, dysrhythmia, CHF, stroke, CKD, asthma/COPD and obesity were classified into the comorbidity group.
CHF, congestive heart failure; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; IHD, ischemic heart disease; PY, person-years; RA, rheumatoid arthritis.