Table 1

Schedule for treatment and outcome measurements

			Treatment period			Follow-up
Items		Screening	Visit 1	Visit 2	Visit 3	Visit 4	Visit 5
Participant agreement		•
Blood sampling agreement		•
Enrolment		•
Demographic history		•
Medical history		•
Blood stasis screening		•
Blood stasis questionnaire			•		•		•
Dysmenorrhoea	Numeric rating scale		•	•	•	•	•
	A shortened version of the McGill pain questionnaire		•	•	•	•	•
	Cox menstrual symptom scale		•	•	•	•	•
Physical examinations		•	•		•
Clinical pathology examination		•	•		•
Confirmation of inclusion and exclusion criteria		•	•
Confirmation of medical history and history of changed treatments			•	•	•
Randomisation			•
Medication			•	•
Adverse event				•	•	•	•
Ultrasonography		•			•
Compliance check				•	•