Therapy persistence for monotherapy, free-drug combinations and fixed combinations
| Duration (days of follow-up) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Initial | Refill prescriptions within 180 days | Refill prescriptions within 360 days | |||||||
| Drugs | Patients† N | 360* (%) | 720* (%) | 1080 (%) | 1440 (%) | 360 (%) | 720 (%) | 1080 (%) | 1440 (%) |
| Monotherapy | 6502 | 63.4 | 52.3 | 45.0 | 40.3 | 86.6 | 80.4 | 76.9 | 74.6 |
| Fixed combination of two drugs | 867 | 64.6 | 52.1 | 45.2 | 39.8 | 87.3 | 79.8 | 76.5 | 74.4 |
| Free combination of two drugs | 663 | 78.7 | 69.1 | 62.7 | 56.4 | 92.2 | 88.0 | 85.0 | 82.8 |
†Patients received at least two antihypertensive prescriptions.